Evidence map›Paper›PMID 34303754›Full record

ReviewAdvanced drug delivery reviews2021

Phytonanomaterials as therapeutic agents and drug delivery carriers.

Ying Xie, Chao Ma, Xin Yang, Jiacheng Wang, Gretchen Long, Jiangbing Zhou

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advanced drug delivery reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Overview of Antimicrobial Biodegradable Polyester-Based Formulations.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying XieDepartment of Neurosurgery, Yale University, New Haven, CT 06510, USA.
Chao MaCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China.
Xin YangSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150090, China.
Jiacheng WangSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150090, China; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225009, China.
Gretchen LongDepartment of Neurosurgery, Yale University, New Haven, CT 06510, USA.
Jiangbing ZhouDepartment of Neurosurgery, Yale University, New Haven, CT 06510, USA; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA. Electronic address: jiangbing.zhou@yale.edu.

Funding

Improved glyburide therapy via acid- triggered release functional nanoparticles and therapeutic imagingR01NS110721 · NINDS · YALE UNIVERSITY · PI SHETH, KEVIN NAVIN, ZHOU, JIANGBING · 2019 to 2023
$1.9M
NINDS NIH HHS R01 NS110721
6 · The paper itself

Abstract

Medicinal plants have been a major resource for drug discovery. Emerging evidence shows that in addition to pharmacologically active components, medicinal plants also contain phytochemical nanomaterials, or phytonanomaterials, which form nanoparticles for drug delivery. In this review, we examine the evidence supporting the existence of phytonanomaterials. Next, we review identification, isolation, and classification of phytonanomaterials, characteristics of phytonanomaterial-derived nanoparticles, and molecular mechanisms of phytonanomaterial assembly. We will then summarize the current progress in exploring phytonanomaterial-derived NPs as therapeutic agents and drug delivery carriers for disease treatment. Last, we will provide perspectives on future discovery and applications of phytonanomaterials.

Indexed as

Drug Delivery SystemsAnimalsHumansNanostructuresPhytochemicalsPhytochemicalsDrug deliveryMedicinal plantsNanoparticlesNanostructural assemblyPhytonanomaterials

Identifiers

PMID34303754
PMCPMC8482412

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.