ArticleOphthalmology2022
Stroke Risk before and after Central Retinal Artery Occlusion: A Population-based Analysis.
Article in Ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Atrial Fibrillation in Retinal Artery Occlusion: A Systematic Review and Meta-Analysis.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Incidence and risk factors associated with ischemic cerebrovascular disease in patients with retinal artery occlusion: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Signals of drug-related retinal artery occlusion: a multi-country retrospective study from a spontaneous reporting system.Frontiers in medicine · 2026Article
- RNF213 c.14429G > A (p.Arg4810Lys) is associated with non-arteritic retinal artery occlusion.Scientific reports · 2025Article
- Amaurosis fugax progressing to retinal artery occlusion with anterior migration of a retrobulbar embolus on orbital color Doppler imaging.American journal of ophthalmology case reports · 2025Article
- High-sensitivity C-reactive protein and risk of retinal artery occlusion and ischaemic stroke: a cross-cohort study.The British journal of ophthalmology · 2025Article
- Ankle-Brachial Index as a Predictor of Acute Ischemic Cerebrovascular Event After Central Retinal Artery Occlusion.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Subsequent Acute Ischemic Stroke in a Patient with Monocular Vision Loss Associated with Isolated Internal Carotid Artery Occlusion: A Case Report.Neurology international · 2024Article
- Retinal Artery Occlusion: A Review of Current Management Practices.Journal of ophthalmic & vision research · 2024Review
- Exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases.Nature biomedical engineering · 2024Article
- Article
- A Triggering Event of Central Retinal Artery Occlusion With Concurrent Ischemic Stroke.Cureus · 2024Article
- Retina-Brain Homology: The Correlation Between Ophthalmic or Retinal Artery Occlusion and Ischemic Stroke.Eye and brain · 2024Review
- Incidence of central retinal artery occlusion peaks in winter season.Frontiers in neurology · 2024Article
- OCTA characteristics in non-arteritic central retinal artery occlusion and correlation with visual acuity.International journal of ophthalmology · 2024Article
- Thrombolytic Therapy for Central Retinal Artery Occlusion in an Academic Multi-Site Stroke Centre.Neuro-ophthalmology (Aeolus Press) · 2024Article
- Causal association of type 2 diabetes with central retinal artery occlusion: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Risk and risk factor of ischemic stroke after acute retinal arterial ischemia.International ophthalmology · 2023Article
- The diagnosis and treatment of central retinal artery occlusion with severe cardio-cerebrovascular disease: a case report.Annals of translational medicine · 2023Article
- Risk Factors and Treatment Strategy for Retinal Vascular Occlusive Diseases.Journal of clinical medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo determine the risk of stroke, transient ischemic attack (TIA), and transient monocular vision loss (TMVL) before and after a central retinal artery occlusion (CRAO).
designPopulation-based, retrospective case series.
participantsPatients diagnosed with a CRAO in Olmsted County, Minnesota, from 1976 to 2016.
methodsPatients living in Olmsted County with a diagnosis code of CRAO from 1976 to 2016 were reviewed. New CRAOs were confirmed, and stroke, TIA, and TMVL events in the 15 days before and after CRAO were recorded.
main outcome measuresIncidence of stroke, TIA, and TMVL events in the 15 days before and after CRAO.
resultsEighty-nine patients with a CRAO were identified, providing an annual incidence of 2.58/100 000 (95% confidence interval [CI], 2.04-3.11). Median age at the time of CRAO was 76 years (range, 46-100 years); 56.2% were male, and 89.9% of the cohort was White. In the 15 days before and after CRAO, there were 2 ischemic strokes (2.2%), 1 hemorrhagic stroke (1.1%), 2 TIAs (2.2%), and 9 TMVL events (10.1%). Starting in 1999, 15 of 45 patients underwent magnetic resonance imaging within 2 months of CRAO. One patient (6.7%) had evidence of asymptomatic diffusion restriction, and 9 patients (60%) had a remote infarct.
conclusionsThis population-based study demonstrated that the risk of symptomatic ischemic stroke is 2.2% in the 15 days before and after a CRAO, which is slightly lower than most studies from tertiary centers. These data should be considered as practice recommendations are developed regarding the urgency of neurovascular workup in patients with acute CRAO.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.