Evidence map›Paper›PMID 34303468›Full record

ArticleThe Journal of investigative dermatology2021

Capturing New Disease Genes in Psoriasis and Other Skin Diseases.

Jefferson K Chen, Ghaidaa Kashgari, Bogi Andersen

Abstract readComment
PubMed Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jefferson K ChenDepartment of Medicine, University of California, Irvine, Irvine, California, USA; Department of Biological Chemistry, University of California, Irvine, Irvine, California, USA.
Ghaidaa KashgariDepartment of Medicine, University of California, Irvine, Irvine, California, USA; Department of Biological Chemistry, University of California, Irvine, Irvine, California, USA.
Bogi AndersenDepartment of Medicine, University of California, Irvine, Irvine, California, USA; Department of Biological Chemistry, University of California, Irvine, Irvine, California, USA. Electronic address: bogi@uci.edu.
University of California, Irvine · US

Funding

Medical Research Council MR/N00017X/1
6 · The paper itself

Abstract

Regulatory regions of the genome harbor most genetic variance associated with skin diseases. Because gene-regulatory networks are cell-type and cell-state specific and are subject to variation from the genetic background, current cell models that link genetic variation to gene expression are imperfect. Emerging single-cell genomics approaches may provide a new approach to understand the genetics of common skin diseases.

Indexed as

PsoriasisSkin DiseasesGene Regulatory NetworksGenomicsHumans

Identifiers

PMID34303468
OpenAlexW3183255525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.