Evidence map›Paper›PMID 34302941›Full record

ArticleExperimental gerontology2021

Resistance exercise training at different loads in frail and healthy older adults: A randomised feasibility trial.

Rebecca Marshall-McKenna, Evan Campbell, Frederick Ho, Matthew Banger, Jane Ireland, Philip Rowe, Christine McAlpine, Kate McArthur, Terence J Quinn, Stuart R Gray

Abstract read
In one paragraph

Article in Experimental gerontology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rebecca Marshall-McKennaInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom of Great Britain and Northern Ireland.
Evan CampbellHealthcare Improvement Scotland, Glasgow, United Kingdom of Great Britain and Northern Ireland.
Frederick HoInstitute of Health and Wellbeing, University of Glasgow, Glasgow G12 8RZ, United Kingdom of Great Britain and Northern Ireland.
Matthew BangerBiomedical Engineering, Graham Hills Building, University of Strathclyde, Glasgow G1 1QE, United Kingdom of Great Britain and Northern Ireland.
Jane IrelandClinical Research Facility, Glasgow Royal Infirmary, Glasgow, United Kingdom of Great Britain and Northern Ireland.
Philip RoweBiomedical Engineering, Graham Hills Building, University of Strathclyde, Glasgow G1 1QE, United Kingdom of Great Britain and Northern Ireland.
Christine McAlpineDepartment of Medicine for the Elderly, Glasgow Royal Infirmary, Glasgow, United Kingdom of Great Britain and Northern Ireland.
Kate McArthurDepartment of Medicine for the Elderly, Glasgow Royal Infirmary, Glasgow, United Kingdom of Great Britain and Northern Ireland.
Terence J QuinnInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom of Great Britain and Northern Ireland; Department of Medicine for the Elderly, Glasgow Royal Infirmary, Glasgow, United Kingdom of Great Britain and Northern Ireland.
Stuart R GrayInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom of Great Britain and Northern Ireland; Department of Health Promotion and Rehabilitation, Lithuanian Sports University, Kaunas, Lithuania. Electronic address: stuart.gray@glasgow.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis trial aimed to determine the feasibility of recruitment, retention, adherence, and safety of a resistance training (RT) intervention to skeletal muscle failure in both frail and non-frail older adults.

designAn 8-week randomised feasibility trial. SETTING AND

participantsOlder adults, with and without frailty, recruited from both clinics and community.

methodsRecruitment was based on the number of participants enrolled from those provided with a Patient Information Sheet (PIS). Retention was based on the number of participants who completed the trial. Adherence was based on the number of RT sessions attended out of 16. Outcomes included frailty (Fried criteria), muscle strength (maximal voluntary contraction), functional abilities (Short Physical Performance battery), quality of life (EQ-5D-5L), activities of daily living (LIADL) and safety (diary).

resultsRecruitment target (n = 60) was achieved within 15 months, 58 were randomised to high (n = 30) or low repetition-load (n = 28) groups. Mean age of participants was 72 years (range 65-93). Adherence and retention rate for the RT intervention was ≥70%. There was one serious adverse experience due to the RT intervention. There were no differences (P > 0.05) in effects of RT on outcome variables between low and high repetition-load groups. CONCLUSIONS AND IMPLICATIONS: Recruitment of frail people was challenging. Older adults performing supervised RT to skeletal muscle failure was feasible and safe, with appropriate caution, and the repetition-load did not appear to influence its efficacy. Future research into the effectiveness of this simplified model of RT is warranted.

Indexed as

Resistance TrainingActivities of Daily LivingAgedAged, 80 and overFeasibility StudiesFrail ElderlyHumansQuality of LifeFeasibilityFrailtyOlder adultsResistance trainingSarcopenia

Identifiers

PMID34302941
PMCPMC8434423

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.