Evidence map›Paper›PMID 34302741›Full record

ArticleCurrent biology : CB2021

Thalamic input to motor cortex facilitates goal-directed action initiation.

Naoya Takahashi, Sara Moberg, Timothy A Zolnik, Julien Catanese, Robert N S Sachdev, Matthew E Larkum, Dieter Jaeger

Abstract read
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Tuft Dendrite Spikes Are Accompanied by Selective Input From Distinct Functional Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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  19. The plasticity of pyramidal neurons in the behaving brain.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naoya TakahashiInstitute for Biology, Humboldt University of Berlin, 10117 Berlin, Germany. Electronic address: naoya.takahashi@u-bordeaux.fr.
Sara MobergEinstein Center for Neurosciences Berlin, 10117 Berlin, Germany.
Timothy A ZolnikInstitute for Biology, Humboldt University of Berlin, 10117 Berlin, Germany.
Julien CataneseDepartment of Biology, Emory University, Atlanta, GA 30322, USA.
Robert N S SachdevInstitute for Biology, Humboldt University of Berlin, 10117 Berlin, Germany.
Matthew E LarkumInstitute for Biology, Humboldt University of Berlin, 10117 Berlin, Germany.
Dieter JaegerDepartment of Biology, Emory University, Atlanta, GA 30322, USA. Electronic address: djaeger@emory.edu.

Funding

Multiscale analysis of how the basal ganglia impact cortical processing in behaving miceR01NS111470 · NINDS · EMORY UNIVERSITY · PI JAEGER, DIETER · 2019 to 2023
$2.4M
MULTISCALE ANALYSIS OF SENSORY-MOTOR CORTICAL GATING IN BEHAVING MICEU01NS094302 · NINDS · EMORY UNIVERSITY · PI JAEGER, DIETER, STANLEY, GARRETT B. · 2015 to 2018
$1.8M
NINDS NIH HHS R01 NS111470NINDS NIH HHS U01 NS094302
6 · The paper itself

Abstract

Prompt execution of planned motor action is essential for survival. The interactions between frontal cortical circuits and the basal ganglia are central to goal-oriented action selection and initiation.

Indexed as

Motor CortexAnimalsAxonsBasal GangliaGoalsMiceNeural PathwaysThalamusanterior lateral motor cortexaxonal calcium imaginggoal-directed actionmotor thalamusreaction timethalamocortical projection

Identifiers

PMID34302741
PMCPMC8478854

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.