Evidence map›Paper›PMID 34302521›Full record

ArticleArchives of orthopaedic and trauma surgery2023

Accelerate postoperative management after scoliosis surgery in healthy and impaired children: intravenous opioid therapy versus epidural therapy.

Katharina Dinter, Henriette Bretschneider, Stefan Zwingenberger, Alexander Disch, Anne Osmers, Oliver Vicent, Falk Thielemann, Jens Seifert, Peter Bernstein

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07737886 (Feasibility, Acceptability, and Preliminary Effects of Virtual Reality for Pain, Anxiety and Recovery Enhancement of Children Post-Scoliosis Surgical Repair), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07737886 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility, Acceptability, and Preliminary Effects of Virtual Reality for Pain, Anxiety and Recovery Enhancement of Children Post-Scoliosis Surgical Repair: A Pilot Randomized Controlled Parallel Trial (VR-SPINE)

TypeinterventionalSponsorSt. Justine's HospitalRan2026 to 2028Enrolled24ConditionsScoliosis PatientsArmsVirtual Reality, Standard medical treatment
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. An Update on Pain Management in Pediatric Spine Surgery.Current reviews in musculoskeletal medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Katharina DinterUniversityCenter for Orthopaedic, Trauma and Plastic Surgery , University Comprehensive Spine Center, University Medicine "Carl Gustav Carus" , TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany. Katharina.Dinter@uniklinikum-dresden.de.ORCID http://orcid.org/0000-0001-7212-0931
Henriette BretschneiderUniversityCenter for Orthopaedic, Trauma and Plastic Surgery , University Comprehensive Spine Center, University Medicine "Carl Gustav Carus" , TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Stefan ZwingenbergerUniversityCenter for Orthopaedic, Trauma and Plastic Surgery , University Comprehensive Spine Center, University Medicine "Carl Gustav Carus" , TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Alexander DischUniversityCenter for Orthopaedic, Trauma and Plastic Surgery , University Comprehensive Spine Center, University Medicine "Carl Gustav Carus" , TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Anne OsmersDepartment of Anesthesiology and Intensive Care Medicine, University Hospital "Carl Gustav Carus", TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Oliver VicentDepartment of Anesthesiology and Intensive Care Medicine, University Hospital "Carl Gustav Carus", TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Falk ThielemannUniversityCenter for Orthopaedic, Trauma and Plastic Surgery , University Comprehensive Spine Center, University Medicine "Carl Gustav Carus" , TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Jens SeifertDepartment of Spine Surgery, AKG Klinik Hohwald GmbH, Hospital for Orthopaedics and Rheumatology, Hohwaldstraße 40, 01844, Neustadt in Sachsen, Germany.
Peter BernsteinUniversityCenter for Orthopaedic, Trauma and Plastic Surgery , University Comprehensive Spine Center, University Medicine "Carl Gustav Carus" , TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
University Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative pain is a major concern following scoliosis surgery. CEA (continuous epidural analgesia) is established in postoperative pain therapy as well as intravenous patient-controlled analgesia (IV-PCA). The purpose of this study was to compare the clinical outcomes of both methods.

methodsWe retrospectively studied 175 children between 8 and 18 years who were subject to posterior scoliosis correction and fusion. Two main cohorts were formed: CEA with local anesthetic and opioids, and IV-PCA with opioids. Both groups further comprised two sub-cohorts: those who were mentally and/or physically healthy (H; n = 93 vs. n = 30) and those who were impaired (I; n = 26 vs. n = 26). The outcome parameters were the demand for pain medication, parameters of mobilization, and the presence of adverse reactions.

resultsHealthy children who received CEA started mobilization 1 day earlier than children with IV-PCA (p = 0.002). First postsurgical defecation was seen earlier in all children who received CEA in both groups (H; Day 4 vs. Day 5, p = 0.011, I; Day 3 vs. Day 5, p = 0.044). Healthy children who received CEA were discharged from hospital 4 days earlier than their IV-PCA counterparts (p < 0.001). No statistically significant difference in postoperative nausea nor in vomiting was identified between groups. Transient neurological irritations were seen in 9.7% of the patients in the CEA group.

conclusionsCEA provides appropriate pain management after scoliosis surgery, regardless of the patient's mental status. It allows earlier postoperative defecation for all patients , as well as shorter hospitalization and an earlier mobilization for healthy patients.

Indexed as

Analgesia, EpiduralScoliosisAnalgesia, Patient-ControlledAnalgesics, OpioidChildHumansPostoperative Nausea and VomitingPostoperative PainRetrospective StudiesAnalgesics, OpioidEpidural analgesiaPainRecoveryScoliosis surgery

Identifiers

PMID34302521
PMCPMC9886629
OpenAlexW3186037307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.