Evidence map›Paper›PMID 34302514›Full record

ArticleExperimental brain research2021

Sensory defunctionalization induced by 8% topical capsaicin treatment in a model of ultraviolet-B-induced cutaneous hyperalgesia.

Silvia Lo Vecchio, Hjalte Holm Andersen, Jesper Elberling, Lars Arendt-Nielsen

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Capsaicin: Emerging Pharmacological and Therapeutic Insights.Current issues in molecular biology · 2024
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Silvia Lo VecchioLaboratory for Experimental Cutaneous Pain and Itch Research, SMI, Department of Health Science and Technology, Center for Neuroplasticity and Pain, Faculty of Medicine, Aalborg University, Fredrik Bajers Vej 7D, 9220, Aalborg, Denmark. slv@hst.aau.dk.ORCID http://orcid.org/0000-0001-6548-2459
Hjalte Holm AndersenLaboratory for Experimental Cutaneous Pain and Itch Research, SMI, Department of Health Science and Technology, Center for Neuroplasticity and Pain, Faculty of Medicine, Aalborg University, Fredrik Bajers Vej 7D, 9220, Aalborg, Denmark.
Jesper ElberlingDepartment of Dermato-Allergology, The Allergy Clinic, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark.
Lars Arendt-NielsenLaboratory for Experimental Cutaneous Pain and Itch Research, SMI, Department of Health Science and Technology, Center for Neuroplasticity and Pain, Faculty of Medicine, Aalborg University, Fredrik Bajers Vej 7D, 9220, Aalborg, Denmark.
Aalborg University · DKGentofte Hospital · DK

Funding

Danish National Research Foundation DNRF121
6 · The paper itself

Abstract

Subpopulations of primary nociceptors (C- and Aδ-fibers), express the TRPV1 receptor for heat and capsaicin. During cutaneous inflammation, these afferents may become sensitized, leading to primary hyperalgesia. It is known that TRPV1

Indexed as

CapsaicinHyperalgesiaHumansNociceptorsPainPain ThresholdCapsaicinCapsaicinC-fibersInflammationNeurogenic inflammationTPRV1Ultraviolet-B irradiation

Identifiers

PMID34302514
OpenAlexW3185505864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.