Evidence map›Paper›PMID 34302504›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Head-to-head comparison of [

Jonathan Kuten, Charles Levine, Ofer Shamni, Sharon Pelles, Ido Wolf, Guy Lahat, Eyal Mishani, Einat Even-Sapir

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 7 pooled it
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 7 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Diagnostic performance of [Frontiers in medicine · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. [European journal of medical research · 2023
    Pooled it
  5. Comparison ofFrontiers in oncology · 2023
    Pooled it
  6. Pooled it
  7. Pooled it
  8. 177Lu-LNC1004 Radioligand Therapy in Patients with End-stage Metastatic Cancers: A Single-Center, Single-Arm, Phase II Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Trial
  9. [Abdominal radiology (New York) · 2026
    Article
  10. Diagnostic performance of [Abdominal radiology (New York) · 2026
    Article
  11. Diagnostic value of [Abdominal radiology (New York) · 2026
    Article
  12. Article
  13. Article
  14. Comparative analysis ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  15. Review
  16. Article
  17. Diagnostic Efficacy of FAPI-PET/CT Versus [Diagnostics (Basel, Switzerland) · 2026
    Review
  18. Review
  19. Article
  20. Asia Oceania journal of nuclear medicine & biology · 2026
    Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jonathan KutenDepartment of Nuclear Medicine, Tel Aviv Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, 6 Weizmann St, 6423906, Tel Aviv, Israel. jonathanku@tlvmc.gov.il.ORCID http://orcid.org/0000-0002-3458-9904
Charles LevineDepartment of Nuclear Medicine, Tel Aviv Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, 6 Weizmann St, 6423906, Tel Aviv, Israel.
Ofer ShamniCyclotron Radiochemistry Unit, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Sharon PellesDivision of Oncology, Tel Aviv Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ido WolfDivision of Oncology, Tel Aviv Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Guy LahatDepartment of Surgery, Tel Aviv Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Eyal MishaniCyclotron Radiochemistry Unit, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Einat Even-SapirDepartment of Nuclear Medicine, Tel Aviv Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, 6 Weizmann St, 6423906, Tel Aviv, Israel.
Tel Aviv University · ILHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background[

methodsWe performed a head-to-head prospective comparison of FAPI and FDG PET/CT in the same group of 13 patients with gastric adenocarcinoma who presented for either initial staging (n = 10) or restaging (n = 3) of disease. Lesion detection and maximum standardized uptake value (SUV

resultsAll ten primary gastric tumors were FAPI-positive (100% detection rate), whereas only five were also FDG-positive (50%). SUV

conclusionsThe findings of this pilot study suggest that FAPI PET/CT outperforms FDG PET/CT in detecting both primary gastric adenocarcinoma and peritoneal carcinomatosis from gastric cancer. FAPI PET/CT also shows promise for monitoring response to treatment in patients with peritoneal carcinomatosis from gastric cancer; however, larger trials are needed to validate these preliminary findings.

Indexed as

AdenocarcinomaStomach NeoplasmsFluorodeoxyglucose F18Gallium RadioisotopesHumansPilot ProjectsPositron Emission Tomography Computed TomographyProspective StudiesQuinolines68Ga-FAPIFluorodeoxyglucose F18Gallium RadioisotopesQuinolines[18F]-FDG[68Ga]Ga-FAPI-04Gastric cancerHead-to-headPeritoneal carcinomatosisPET/CT

Identifiers

PMID34302504
PMCPMC8803763
OpenAlexW3185979786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.