Evidence map›Paper›PMID 34302314›Full record

ArticleJournal of genetic counseling2022

Barriers to family history knowledge and family communication among LGBTQ+ individuals in the context of hereditary cancer risk assessment.

Bradley A Rolf, Jennifer L Schneider, Laura M Amendola, James V Davis, Kathleen F Mittendorf, Mark A Schmidt, Gail P Jarvik, Benjamin S Wilfond, Katrina A B Goddard, Jessica Ezzell Hunter

Open access · greenAbstract read
In one paragraph

Article in Journal of genetic counseling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Young Women's Perspectives on Being Screened for Hereditary Breast and Ovarian Cancer Risk During Routine Primary Care.Women's health issues : official publication of the Jacobs Institute of Women's Health
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Bradley A RolfDepartment of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA, USA.
Jennifer L SchneiderCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Laura M AmendolaDepartment of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA, USA.
James V DavisCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Kathleen F MittendorfDepartment of Translational and Applied Genomics, Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Mark A SchmidtCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Gail P JarvikDepartment of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA, USA.
Benjamin S WilfondTreuman Katz Center for Pediatric Bioethics, Seattle Children's Hospital and Research Institute, Seattle, WA, USA.
Katrina A B GoddardDepartment of Translational and Applied Genomics, Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Jessica Ezzell HunterDepartment of Translational and Applied Genomics, Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Kaiser Permanente Center for Health Research · USUniversity of Washington Medical Center · USUniversity of Washington · US

Funding

Exome sequencing in Diverse Populations in Colorado & OregonU01HG007292 · NHGRI · KAISER FOUNDATION RESEARCH INSTITUTE · PI LEO, MICHAEL C, WILFOND, BENJAMIN SIMON · 2017 to 2021
$15.7M
Evolving Our Partnership: The CSER2 Centralized Support Coordinating CenterU24HG007307 · NHGRI · UNIVERSITY OF WASHINGTON · PI FULLERTON, STEPHANIE MALIA, JARVIK, GAIL PAIRITZ · 2017 to 2021
$5.8M
NHGRI NIH HHS U01 HG007292NHGRI NIH HHS U24 HG007307
6 · The paper itself

Abstract

Openness about identity as lesbian, gay, bisexual, transgender, queer, and other sexual orientations and gender identities (LGBTQ+) may cause strain on relationships between family members, which could lead to limited knowledge of cancer family history and reduced communication with family members. As a result, members of the LGBTQ+ community may have more difficulty accessing genetic counseling services for inherited cancer risk. We applied a mixed-methods approach to explore potential barriers to knowledge of cancer family history and family communication among participants of the Cancer Health Assessments Reaching Many (CHARM) study who self-identified as LGBTQ+. We assessed perceptions of family functioning and communication of genetic test results to family members using survey tools and supplemented these data with 20 in-depth interviews to further assess participant perspectives and experiences. LGBTQ+ participants were more likely to report unhealthy family functioning on the survey tool, and some interviewees endorsed that openness about their LGBTQ+ identity led to strained family relationships and reduced communication about their family history of cancer. Overall, this study identified barriers that may be faced by members of the LGBTQ+ community which could limit their ability to access genetic counseling services for inherited cancer risk.

Indexed as

Homosexuality, FemaleNeoplasmsSexual and Gender MinoritiesCommunicationFemaleGenetic Predisposition to DiseaseHumansRisk AssessmentCultural competencefamily historygenetic counselinghereditary cancerLGBTQ+risk assessment

Identifiers

PMID34302314
PMCPMC8783924
OpenAlexW3186253515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.