ReviewSkeletal radiology2022
Update on the imaging features of the enchondromatosis syndromes.
Review in Skeletal radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Intraosseous tumours of the knee.Skeletal radiology · 2026Review
- [Primary malignant bone tumours-part II].Radiologie (Heidelberg, Germany) · 2026Review
- Surgical resection for multiple enchondromas in the hand: a case report.International journal of surgery case reports · 2026Article
- Intraosseous Pneumatocysts of the Scapula Mimicking Bone Tumors: A Report of Two Rare Cases Along with Elucidation of Their Etiology.Diseases (Basel, Switzerland) · 2025Article
- Hereditary multiple exostoses: an educational review.Insights into imaging · 2025Article
- A rare presentation of Maffucci syndrome: A case report and literature review.Experimental and therapeutic medicine · 2023Article
- A Rare Co-Occurrence of Maffucci Syndrome and Astrocytoma with IDH1 R132H Mutation: A Case Report.Medicina (Kaunas, Lithuania) · 2023Article
- Imaging Aspects of Enchondromas in Pediatric Patients.Current health sciences journalArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ollier disease and Maffucci syndrome are the commonest enchondromatosis subtypes, arising from non-hereditary mutations in the IDH1 and IDH2 genes, presenting in childhood and being characterised by multiple enchondromas. Maffucci syndrome also includes multiple soft tissue haemangiomas. Aside from developing bony masses, osseous deformity and pathological fracture, ~ 40% of these patients develop secondary central chondrosarcoma, and there is increased risk of non-skeletal malignancies such as gliomas and mesenchymal ovarian tumours. In this review, we outline the molecular genetics, pathology and multimodality imaging features of solitary enchondroma, Ollier disease and Maffucci syndrome, along with their associated skeletal complications, in particular secondary chondrosarcoma. Given the lifelong risk of malignancy, imaging follow-up will also be explored. Metachondromatosis, a rare enchondromatosis subtype characterised by enchondromas and exostoses, will also be briefly outlined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.