Evidence map›Paper›PMID 34302052›Full record

ArticleScientific reports2021

Oxidative stress parameters as biomarkers of bladder cancer development and progression.

Paulina Wigner, Beata Szymańska, Michał Bijak, Ewa Sawicka, Paweł Kowal, Zofia Marchewka, Joanna Saluk-Bijak

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

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  10. Impact of anthracycline-based chemotherapy on RB1 gene methylation in peripheral blood leukocytes and biomarkers of oxidative stress and inflammation in sarcoma patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Paulina WignerDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236, Lodz, Poland. paulina.wigner@biol.uni.lodz.pl.
Beata SzymańskaDepartment of Toxicology, Faculty of Pharmacy and Division of Laboratory, Wroclaw Medical University, Borowska 211, 50-556, Wrocław, Poland.
Michał BijakBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, 90-136, Lodz, Poland.
Ewa SawickaDepartment of Toxicology, Faculty of Pharmacy and Division of Laboratory, Wroclaw Medical University, Borowska 211, 50-556, Wrocław, Poland.
Paweł KowalDepartment and Clinic of Urology and Urological Oncology, Faculty of Postgraduate Medical Training, Wroclaw Medical University, Kamieńskiego 73a, 51-124, Wrocław, Poland.
Zofia MarchewkaDepartment of Toxicology, Faculty of Pharmacy and Division of Laboratory, Wroclaw Medical University, Borowska 211, 50-556, Wrocław, Poland.
Joanna Saluk-BijakDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236, Lodz, Poland.
Wroclaw Medical University · PLUniversity of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidemiological studies confirm that the overproduction of free radical is an important factor of cancer induction as well as development, and loss of antioxidant systems efficiency is associated with an increased risk of carcinogenesis. While bladder cancer is the fourth most common type of cancer all over the world, there is little evidence of the advancing changes in oxidative/nitrative stress during the progression of bladder cancer. Our study aimed to investigate the plasma levels of typical markers of oxidative/nitrative stress depending on the clinical classification of bladder cancer differentiation and infiltration degree. We examined 40 patients with newly diagnosed bladder cancer and 20 healthy volunteers as a control group. We analysed the plasma levels of protein carbonyls, thiol groups, 3-nitrotyrosine, lipid peroxidation, as well as non-enzymatic plasma antioxidant capacity using DPPH

Indexed as

AdultAntioxidantsBiomarkersCase-Control StudiesDisease ProgressionFemaleFree RadicalsHumansLipid PeroxidationMaleMiddle AgedOxidative StressSulfhydryl CompoundsTyrosineUrinary Bladder Neoplasms3-nitrotyrosineAntioxidantsBiomarkersFree RadicalsSulfhydryl CompoundsTyrosine

Identifiers

PMID34302052
PMCPMC8302678
OpenAlexW3184937005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.