Evidence map›Paper›PMID 34302007›Full record

ArticleScientific reports2021

Intestinal anti-inflammatory activity of Ulva ohnoi oil in DSS-induced experimental mouse model.

JeongEun Kang, JiSun Park, Jung-Kil Seo, WonHyung Choi, SooCheol Choi, Ju-Hyoung Kim, In-Ah Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. An assessment of vaping-induced inflammation and toxicity: A feasibility study using a 2-stage zebrafish and mouse platform.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
    Article
  5. Frontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

JeongEun KangDepartment of Chemistry, Kunsan National University, Gunsan, 54150, Korea.
JiSun ParkDepartment of Chemistry, Kunsan National University, Gunsan, 54150, Korea.
Jung-Kil SeoDepartment of Food Science and Bitoechnology, Kunsan National University, Gunsan, 54150, Korea.
WonHyung ChoiDepartment of Infection Biology, School of Medicine, Wonkwang University, Iksan, 54538, Korea.
SooCheol ChoiDepartment of Chemistry, Kunsan National University, Gunsan, 54150, Korea.
Ju-Hyoung KimDepartment of Aquaculture and Aquatic Science, Kunsan National University, Gunsan, 54150, Korea.
In-Ah LeeDepartment of Chemistry, Kunsan National University, Gunsan, 54150, Korea. leeinah@kunsan.ac.kr.
Kunsan National University · KRWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to examine the physiological activity of Ulva ohnoi, some of which may be used for food or natural products but could disturbing coastal ecosystems due to large scale green-tide, to check values of U. ohnoi oil through experimental results. U. ohnoi oil was extracted from bulk of Ulva biomass to confirm its antioxidant and antibacterial activity, and the efficacy of U. ohnoi oil in the state of inflammation was confirmed through animal experiments. To confirm the anti-inflammatory effect, a mouse model induced with DSS was used. As a result of measuring NO using plasma after induction of inflammation, the amount of NO produced in the U. ohnoi oil group was decreased compared to the control group. Expression of inflammatory cytokines TNF-α, IL-6, and IL-1β was decreased compared to the control group. As a result of observing H&E staining, lower crypt loss and inflammatory cell infiltration were found in the U. ohnoi oil group compared to the control group. Consequently, U. ohnoi oil appears to have great anti-inflammatory properties.

Indexed as

AnimalsAnti-Inflammatory AgentsCytokinesDextran SulfateDisease Models, AnimalInflammationIntestinesMicePlant ExtractsPlant OilsUlvaAnti-Inflammatory AgentsCytokinesDextran SulfatePlant ExtractsPlant Oils

Identifiers

PMID34302007
PMCPMC8302574
OpenAlexW3184319450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.