Evidence map›Paper›PMID 34302002›Full record

ArticleScientific reports2021

Spatio-temporal biodistribution of

Naomi S Sta Maria, Leslie A Khawli, Vyshnavi Pachipulusu, Sharon W Lin, Long Zheng, Daniel Cohrs, Xiaodan Liu, Peisheng Hu, Alan L Epstein, Russell E Jacobs

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. In vivo tracking of ex-vivo-generatedMolecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Naomi S Sta MariaDepartment of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, ZNI 117, Los Angeles, CA, 90033, USA. nstamari@usc.edu.
Leslie A KhawliDepartment of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Ave, HMR 205, Los Angeles, CA, 9033, USA.
Vyshnavi PachipulusuDepartment of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Ave, HMR 205, Los Angeles, CA, 9033, USA.
Sharon W LinDepartment of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, ZNI 117, Los Angeles, CA, 90033, USA.
Long ZhengDepartment of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Ave, HMR 205, Los Angeles, CA, 9033, USA.
Daniel CohrsDepartment of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Ave, HMR 205, Los Angeles, CA, 9033, USA.
Xiaodan LiuDepartment of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, ZNI 117, Los Angeles, CA, 90033, USA.
Peisheng HuDepartment of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Ave, HMR 205, Los Angeles, CA, 9033, USA.
Alan L EpsteinDepartment of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Ave, HMR 205, Los Angeles, CA, 9033, USA.
Russell E JacobsDepartment of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, ZNI 117, Los Angeles, CA, 90033, USA.
University of Southern California · US

Funding

USC/CHLA Summer Oncology Research Fellowship (SORF) Program for Medical StudentsR25CA225513 · NCI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI ANAT ERDREICH-EPSTEIN, WIJBE MARTIN KAST · 2019 to 2026
$1.7M
NCI NIH HHS R25 CA225513
6 · The paper itself

Abstract

Quantitative in vivo monitoring of cell biodistribution offers assessment of treatment efficacy in real-time and can provide guidance for further optimization of chimeric antigen receptor (CAR) modified cell therapy. We evaluated the utility of a non-invasive, serial

Indexed as

AnimalsCell Line, TumorMaleMiceMice, Inbred NODMice, SCIDNeoplasmsOxyquinolinePositron-Emission TomographyRadioisotopesReceptors, Antigen, T-CellReceptors, Chimeric AntigenTissue DistributionT-LymphocytesZirconiumOxyquinolineRadioisotopesReceptors, Antigen, T-CellReceptors, Chimeric AntigenZirconium

Identifiers

PMID34302002
PMCPMC8302724
OpenAlexW3186237510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.