Evidence map›Paper›PMID 34301944›Full record

ArticleNature communications2021

Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks.

Raziye Karapinar, Jan Claudius Schwitalla, Dennis Eickelbeck, Johanna Pakusch, Brix Mücher, Michelle Grömmke, Tatjana Surdin, Thomas Knöpfel, Melanie D Mark, Ida Siveke and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Optogenetics at the presynapse.Nature neuroscience · 2022
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Raziye Karapinar *Department of Zoology and Neurobiology, Ruhr-University Bochum, Bochum, Germany.
Jan Claudius Schwitalla *Behavioral Neuroscience, Ruhr-University Bochum, Bochum, Germany.ORCID 0000-0001-5426-0359
Dennis Eickelbeck *Department of Zoology and Neurobiology, Ruhr-University Bochum, Bochum, Germany.
Johanna PakuschBehavioral Neuroscience, Ruhr-University Bochum, Bochum, Germany.ORCID 0000-0003-3768-7224
Brix MücherDepartment of Zoology and Neurobiology, Ruhr-University Bochum, Bochum, Germany.
Michelle GrömmkeBehavioral Neuroscience, Ruhr-University Bochum, Bochum, Germany.
Tatjana SurdinDepartment of Zoology and Neurobiology, Ruhr-University Bochum, Bochum, Germany.ORCID 0000-0003-0667-1326
Thomas KnöpfelLaboratory of Optogenetics and Circuit Neuroscience, Imperial College London, London, UK.
Melanie D MarkBehavioral Neuroscience, Ruhr-University Bochum, Bochum, Germany. melanie.mark@rub.de.ORCID 0000-0002-2788-6003
Ida SivekeDepartment of Zoology and Neurobiology, Ruhr-University Bochum, Bochum, Germany.
Stefan HerlitzeDepartment of Zoology and Neurobiology, Ruhr-University Bochum, Bochum, Germany. sxh106@gmail.com.ORCID 0000-0003-1785-0450
Ruhr University Bochum · DEThe Francis Crick Institute · GBUniversity Hospitals of the Ruhr-University of Bochum · DEGerman Cancer Research Center · DEImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opn7b is a non-visual G protein-coupled receptor expressed in zebrafish. Here we find that Opn7b expressed in HEK cells constitutively activates the G

Indexed as

AnimalsGTP-Binding ProteinsHEK293 CellsHumansMiceMice, Inbred C57BLNeuronsOpsinsOptogeneticsPyramidal CellsReceptors, G-Protein-CoupledSignal TransductionSomatosensory CortexSynapsesZebrafishZebrafish ProteinsGTP-Binding ProteinsOpsinsReceptors, G-Protein-CoupledZebrafish Proteins

Identifiers

PMID34301944
PMCPMC8302595
OpenAlexW3185668987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.