Evidence map›Paper›PMID 34301869›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Mechanotaxis directs

Marco J Kühn, Lorenzo Talà, Yuki F Inclan, Ramiro Patino, Xavier Pierrat, Iscia Vos, Zainebe Al-Mayyah, Henriette Macmillan, Jose Negrete, Joanne N Engel and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 103 citations in OpenAlex.

  1. Article
  2. Distinct roles of PilI and ChpC inApplied and environmental microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Marco J KühnInstitute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-7199-575X
Lorenzo TalàInstitute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-3628-3706
Yuki F InclanDepartment of Medicine, University of California, San Francisco, CA 94143.
Ramiro PatinoDepartment of Medicine, University of California, San Francisco, CA 94143.
Xavier PierratInstitute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-3522-2514
Iscia VosInstitute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Zainebe Al-MayyahInstitute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Henriette MacmillanDepartment of Medicine, University of California, San Francisco, CA 94143.ORCID 0000-0001-8171-5072
Jose NegreteInstitute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-8897-5907
Joanne N EngelDepartment of Medicine, University of California, San Francisco, CA 94143; joanne.engel@ucsf.edu alexandre.persat@epfl.ch.ORCID 0000-0002-2168-9711
Alexandre PersatInstitute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland; joanne.engel@ucsf.edu alexandre.persat@epfl.ch.ORCID 0000-0001-8426-8255
École Polytechnique Fédérale de Lausanne · CHUniversity of California, San Francisco · US

Funding

Adapting to a changing environment: How surface contact induces virulence factor production in Pseudomonas aeruginosaR01AI129547 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ENGEL, JOANNE N. · 2017 to 2020
$1.6M
NIAID NIH HHS R01 AI129547
6 · The paper itself

Abstract

The opportunistic pathogen

Indexed as

ChemotaxisGene Expression Regulation, BacterialMechanotransduction, CellularBacterial ProteinsCell MovementFimbriae, BacterialFimbriae ProteinsPseudomonas aeruginosaSignal TransductionBacterial ProteinsFimbriae Proteinschemotaxismechanosensingmotilitytwitchingtype IV pili

Identifiers

PMID34301869
PMCPMC8325320
OpenAlexW3184237505

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.