Evidence map›Paper›PMID 34301848›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

Overexpression of the

Daniel J Perry, Leeana D Peters, Priya Saikumar Lakshmi, Lin Zhang, Zhao Han, Clive H Wasserfall, Clayton E Mathews, Mark A Atkinson, Todd M Brusko

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. SNP inInternational journal of molecular sciences · 2023
    Article
  5. eLife · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Daniel J PerryDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.ORCID 0000-0002-0607-2238
Leeana D PetersDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.ORCID 0000-0002-7878-0014
Priya Saikumar LakshmiDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.ORCID 0000-0001-9446-5770
Lin ZhangDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.
Zhao HanDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.ORCID 0000-0002-0743-6806
Clive H WasserfallDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.ORCID 0000-0002-3522-8932
Clayton E MathewsDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.ORCID 0000-0002-8817-6355
Mark A AtkinsonDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and.
Todd M BruskoDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL; and tbrusko@ufl.edu.ORCID 0000-0003-2878-9296
University of Florida · US

Funding

Project 3P01AI042288 · NIAID · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 1997 to 2026
$32.9M
The CD226 costimulatory axis in type 1 diabetesR01DK106191 · NIDDK · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 2016 to 2026
$4.4M
Genetic Regulation of Human Beta Cell DestructionUC4DK104194 · NIDDK · UNIVERSITY OF FLORIDA · PI MATHEWS, CLAYTON E · 2014 to 2014
$3.1M
Engineering a Human Microphysiological System for the Characterization of Islet-Immune InteractionsUH3DK122638 · NIDDK · UNIVERSITY OF FLORIDA · PI AGARWAL, ASHUTOSH, BRUSKO, TODD MICHAEL · 2021 to 2023
$3.0M
Engineering a Human Microphysiological System for the Characterization of Islet-Immune InteractionsUG3DK122638 · NIDDK · UNIVERSITY OF FLORIDA · PI AGARWAL, ASHUTOSH, BRUSKO, TODD MICHAEL · 2019 to 2020
$2.1M
Interdisciplinary Graduate Program in Type 1 Diabetes and Biomedical EngineeringT32DK108736 · NIDDK · UNIVERSITY OF FLORIDA · PI MARK A. ATKINSON, Benjamin George Keselowsky · 2017 to 2026
$1.9M
NIAID NIH HHS P01 AI042288NIDDK NIH HHS R01 DK106191NIDDK NIH HHS T32 DK108736NIDDK NIH HHS UC4 DK104194NIDDK NIH HHS UG3 DK122638NIDDK NIH HHS UH3 DK122638
6 · The paper itself

Abstract

A missense mutation (R620W) of protein tyrosine phosphatase nonreceptor type 22 (

Indexed as

AutoimmunityCell DifferentiationCell ProliferationCells, CulturedGene Expression RegulationGenetic VariationHumansImmune ToleranceImmunologic MemoryLymphocyte ActivationMutationProtein Tyrosine Phosphatase, Non-Receptor Type 22Signaling Lymphocytic Activation Molecule Associated ProteinT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsProtein Tyrosine Phosphatase, Non-Receptor Type 22PTPN22 protein, humanSH2D1A protein, humanSignaling Lymphocytic Activation Molecule Associated Protein

Identifiers

PMID34301848
PMCPMC8323970
OpenAlexW3183394388

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.