Evidence map›Paper›PMID 34301796›Full record

ArticleJournal of epidemiology and community health2022

Substitutions of physical activity, sedentary behaviour and sleep: associations with mental health in middle-aged and elderly persons.

Amy Hofman, Trudy Voortman, M Arfan Ikram, Annemarie I Luik

Open access · hybridAbstract read
In one paragraph

Article in Journal of epidemiology and community health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  9. Objective physical activity and Alzheimer's disease burden in the population-based Rotterdam Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amy HofmanDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Zuid-Holland, Netherlands.
Trudy VoortmanDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Zuid-Holland, Netherlands.ORCID 0000-0003-2830-6813
M Arfan IkramDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Zuid-Holland, Netherlands.
Annemarie I LuikDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Zuid-Holland, Netherlands a.luik@erasmusmc.nl.ORCID 0000-0001-7517-197X
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical activity, sedentary behaviour and sleep are potential risk factors of mental health disorders, but previous studies have not considered the dependency between these activity domains. Therefore, we examined the associations of reallocations of time among older adults' physical activity, sedentary behaviour and sleep with depressive and anxiety symptoms using compositional isotemporal substitution analyses.

methodsWe included 1943 participants (mean age 71 years, SD: 9; 52% women) from the population-based Rotterdam Study. Between 2011 and 2016, we collected accelerometer data (mean duration 5.8 days, SD: 0.4) on physical activity, sedentary behaviour and sleep and self-reported data on depressive symptoms and anxiety.

resultsA reallocation of 30 min more moderate-to-vigorous physical activity was associated with a -0.55 (95% CI -1.04 to -0.06) points lower depressive symptoms score when replacing sleep and a -0.59 (95% CI -1.06 to -0.12) points lower score when replacing sedentary behaviour, but not when replacing light physical activity (-0.70, 95% CI -1.63 to 0.24). No associations were found for anxiety.

conclusionReplacing sedentary behaviour or sleep with more moderate-to-vigorous physical activity was associated with less depressive symptoms, suggesting that mainly intensive types of physical activity are important for middle-aged and older adults in relation to depressive symptoms.

Indexed as

Mental HealthSedentary BehaviorAccelerometryAgedCross-Sectional StudiesExerciseFemaleHumansMaleMiddle AgedSleepAnxietydepressionexercisemental healthsleep

Identifiers

PMID34301796
PMCPMC8762024
OpenAlexW3184562403

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.