ArticleeNeuro
General Anesthesia Disrupts Complex Cortical Dynamics in Response to Intracranial Electrical Stimulation in Rats.
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 59 citations in OpenAlex.
- Cellular and Microcircuit Mechanisms of Anesthetic Disruption of Conscious-State Organization.Cells · 2026Review
- Thermodynamics of consciousness: Non-equilibrium brain dynamics track conscious states.Cell reports · 2026Article
- Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans.PLoS biology · 2025Article
- Article
- Macroscale Traveling Waves Evoked by Single-Pulse Stimulation of the Human Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Anesthesia alters complexity of spontaneous and stimulus-related neuronal firing patterns in rat visual cortex.Neuroscience · 2025Article
- Sleep-like cortical dynamics during wakefulness and their network effects following brain injury.Nature communications · 2024Review
- Consciousness and sleep.Neuron · 2024Review
- Exploring effects of anesthesia on complexity, differentiation, and integrated information in rat EEG.Neuroscience of consciousness · 2024Article
- Microstimulation reveals anesthetic state-dependent effective connectivity of neurons in cerebral cortex.Frontiers in neuroscience · 2024Article
- Complexity and 1/f slope jointly reflect brain states.Scientific reports · 2023Article
- Whole-brain analyses indicate the impairment of posterior integration and thalamo-frontotemporal broadcasting in disorders of consciousness.Human brain mapping · 2023Article
- Article
- Cortico-thalamo-cortical interactions modulate electrically evoked EEG responses in mice.eLife · 2023Article
- Article
- Variability of Single Pulse Electrical Stimulation Responses Recorded with Intracranial Electroencephalography in Epileptic Patients.Brain topography · 2023Article
- Ketamine and sleep modulate neural complexity dynamics in cats.The European journal of neuroscience · 2022Article
- Spontaneous neuronal avalanches as a correlate of access consciousness.Frontiers in psychology · 2022Article
- Capacity for consciousness under ketamine anaesthesia is selectively associated with activity in posteromedial cortex in rats.Neuroscience of consciousness · 2022Article
- Spontaneous and Perturbational Complexity in Cortical Cultures.Brain sciences · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The capacity of human brain to sustain complex cortical dynamics appears to be strongly associated with conscious experience and consistently drops when consciousness fades. For example, several recent studies in humans found a remarkable reduction of the spatiotemporal complexity of cortical responses to local stimulation during dreamless sleep, general anesthesia, and coma. However, this perturbational complexity has never been directly estimated in non-human animals
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.