Evidence map›Paper›PMID 34301665›Full record

SynthesisBMJ open2021

Multimorbidity in Latin America and the Caribbean: a systematic review and meta-analysis.

Alessandra M Huaquía-Díaz, Tarick S Chalán-Dávila, Rodrigo M Carrillo-Larco, Antonio Bernabe-Ortiz

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. An innovative multimorbidity patient-centered care model in Chile: implementation evaluation results.Archives of public health = Archives belges de sante publique · 2025
    Article
  6. Article
  7. Multimorbidity and its association with mental health in an adult population of Peru.Revista peruana de medicina experimental y salud publica · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Multimorbidity.Nature reviews. Disease primers · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessandra M Huaquía-DíazUniversidad Científica del Sur, Lima, Peru.
Tarick S Chalán-DávilaUniversidad Científica del Sur, Lima, Peru.
Rodrigo M Carrillo-LarcoDepartment of Epidemiology and Bisotatistics, School of Public Health, Imperial College London, London, UK.
Antonio Bernabe-OrtizUniversidad Científica del Sur, Lima, Peru antonio.bernabe@upch.pe.ORCID 0000-0002-6834-1376

Funding

Wellcome TrustWellcome Trust 214185/Z/18/Z
6 · The paper itself

Abstract

objectiveTo estimate the pooled prevalence of multimorbidity (≥2 non-communicable diseases in the same individual) among adults of the general population of Latin American and the Caribbean (LAC).

designSystematic review and meta-analysis. DATA SOURCES: MEDLINE, Embase, Global Health, Scopus and LILACS up to 1 July 2020. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: The outcome was the prevalence of multimorbidity. Reports were selected whether they enrolled adult individuals (age ≥18 years) from the general population. DATA EXTRACTION AND SYNTHESIS: Reviewers extracted relevant data and assessed risk of bias independently. A random-effects meta-analysis was conducted to report pooled prevalence estimates of multimorbidity; pooled estimates by pre-specified subgroups (eg, national studies) were also pursued.

resultsFrom 5830 results, we selected 28 reports, mostly from Brazil and 16 were based on a nationally representative sample. From the 28 selected reports, 26 were further included in the meta-analysis revealing a pooled multimorbidity prevalence of 43% (95% CI: 35% to 51%; I

conclusionsOur results complement and advance those from global efforts by incorporating much more reports from LAC. We revealed a larger presence of multimorbidity in LAC than previously reported. PROSPERO REGISTRATION NUMBER: CRD42020196177.

Indexed as

MultimorbidityAdolescentBrazilCaribbean RegionHumansLatin AmericaPrevalencediabetes & endocrinologyepidemiologyhypertensionpublic health

Identifiers

PMID34301665
PMCPMC8311299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.