ArticleHarm reduction journal2021
Willingness to use a wearable device capable of detecting and reversing overdose among people who use opioids in Philadelphia.
Article in Harm reduction journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04530591 (A Proof of Concept, Randomized, Single Center Study on Frameworks for Wearable Devices to Sense and Respond to Opioid Overdoses), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Proof of Concept, Randomized, Single Center Study on Frameworks for Wearable Devices to Sense and Respond to Opioid Overdoses
Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Acceptability and usability of a respiratory biosensor for drug overdose detection and first responder notification: a qualitative evaluation of perspectives from people who use drugs and wider stakeholders.Harm reduction journal · 2026Article
- Utilization and Feasibility of a Wearable Device in Patients With Sedative Effects of Drugs: Protocol for a Prospective Observational Study for the Advanced Respiratory Monitoring Events in Drug Toxicity (ARM-ED) Study.JMIR research protocols · 2026Observational
- Feasibility and Form Factor Validation of Reflective Shoulder-Mounted Pulse Oximeter in Patients with Suspected Sleep Apnea.Sensors (Basel, Switzerland) · 2026Article
- Barriers to translating continuous monitoring technologies for preventative medicine.Nature biomedical engineering · 2025Review
- Use of a Shoulder-Mounted Wearable Sensor Prototype Designed to Detect Opioid-Related Overdose: A Qualitative User Experience Study.Journal of medical Internet research · 2025Article
- Article
- An implantable system for opioid safety.Device · 2024Article
- Overdose Detection Among High-Risk Opioid Users Via a Wearable Chest Sensor in a Supervised Injecting Facility: Protocol for an Observational Study.JMIR research protocols · 2024Observational
- Users' Acceptability and Perceived Efficacy of mHealth for Opioid Use Disorder: Scoping Review.JMIR mHealth and uHealth · 2024Article
- Opioid Overdose Detection in a Murine Model Using a Custom-Designed Photoplethysmography Device.Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research · 2023Article
- Safety in solitude? Competing risks and drivers of solitary drug use among women who inject drugs and implications for overdose detection.Addiction (Abingdon, England) · 2023Article
- The acceptability of overdose alert and response technologies: introducing the TPOM-ODART framework.Harm reduction journal · 2023Article
- Overdose Alert and Response Technologies: State-of-the-art Review.Journal of medical Internet research · 2023Review
- Overdose Detection Technologies to Reduce Solitary Overdose Deaths: A Literature Review.International journal of environmental research and public health · 2023Review
- Reducing opioid related deaths for individuals who are at high risk of death from overdose: a co-production study with people housed within prison and hostel accommodation during Covid-19.Frontiers in public health · 2023Article
- Digital Biomarker Applications Across the Spectrum of Opioid Use Disorder.Cogent mental health · 2023Article
- Treatment of opioid overdose: current approaches and recent advances.Psychopharmacology · 2022Review
- Perceptions on wearable sensor-based interventions for monitoring of opioid therapy: A qualitative study.Frontiers in digital health · 2022Article
- Wearable biosensors have the potential to monitor physiological changes associated with opioid overdose among people who use drugs: A proof-of-concept study in a real-world setting.Drug and alcohol dependence · 2021Article
- Closed-loop wearable naloxone injector system.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of opioid-related overdose deaths has been rising for 30 years and has been further exacerbated amidst the COVID-19 pandemic. Naloxone can reverse opioid overdose, lower death rates, and enable a transition to medication for opioid use disorder. Though current formulations for community use of naloxone have been shown to be safe and effective public health interventions, they rely on bystander presence. We sought to understand the preferences and minimum necessary conditions for wearing a device capable of sensing and reversing opioid overdose among people who regularly use opioids.
methodsWe conducted a combined cross-sectional survey and semi-structured interview at a respite center, shelter, and syringe exchange drop-in program in Philadelphia, Pennsylvania, USA, during the COVID-19 pandemic in August and September 2020. The primary aim was to explore the proportion of participants who would use a wearable device to detect and reverse overdose. Preferences regarding designs and functionalities were collected via a questionnaire with items having Likert-based response options and a semi-structured interview intended to elicit feedback on prototype designs. Independent variables included demographics, opioid use habits, and previous experience with overdose.
resultsA total of 97 adults with an opioid use history of at least 3 months were interviewed. A majority of survey participants (76%) reported a willingness to use a device capable of detecting an overdose and automatically administering a reversal agent upon initial survey. When reflecting on the prototype, most respondents (75.5%) reported that they would wear the device always or most of the time. Respondents indicated discreetness and comfort as important factors that increased their chance of uptake. Respondents suggested that people experiencing homelessness and those with low tolerance for opioids would be in greatest need of the device.
conclusionsThe majority of people sampled with a history of opioid use in an urban setting were interested in having access to a device capable of detecting and reversing an opioid overdose. Participants emphasized privacy and comfort as the most important factors influencing their willingness to use such a device.
trial registrationNCT04530591.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.