Evidence map›Paper›PMID 34301151›Full record

ArticleThe Annals of pharmacotherapy2022

Addressing Barriers to Reducing Prescribing and Implementing Deprescribing of Sedative-Hypnotics in Primary Care.

Lisa Burry, Justin Turner, Timothy Morgenthaler, Cara Tannenbaum, Hyung J Cho, Evelyn Gathecha, Flora Kisuule, Abi Vijenthira, Christine Soong

Open access · greenAbstract read
In one paragraph

Article in The Annals of pharmacotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Lisa BurrySinai Health System, Toronto, Ontario, Canada.ORCID 0000-0002-6545-3890
Justin TurnerUniversité de Montréal, Montréal, Québec, Canada.ORCID 0000-0003-0613-108X
Timothy MorgenthalerMayo Clinic, Rochester, MN, USA.
Cara TannenbaumUniversité de Montréal, Montréal, Québec, Canada.
Hyung J ChoIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Evelyn GathechaJohns Hopkins Bayview Medical Center, Baltimore, MD, USA.
Flora KisuuleJohns Hopkins Bayview Medical Center, Baltimore, MD, USA.
Abi VijenthiraUniversity of Toronto, Ontario, Canada.
Christine SoongSinai Health System, Toronto, Ontario, Canada.
University of Toronto · CAJohns Hopkins University · USInstitut Universitaire de Gériatrie de Montréal · CALown Institute · USMayo Clinic in Arizona · USUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe interventions that target patient, provider, and system barriers to sedative-hypnotic (SH) deprescribing in the community and suggest strategies for healthcare teams. DATA SOURCES: Ovid MEDLINE ALL and EMBASE Classic + EMBASE (March 10, 2021). STUDY SELECTION AND DATA EXTRACTION: English-language studies in primary care settings. DATA SYNTHESIS: 20 studies were themed as patient-related and prescriber inertia, physician skills and awareness, and health system constraints. Patient education strategies reduced SH dose for 10% to 62% of participants, leading to discontinuation in 13% to 80% of participants. Policy interventions reduced targeted medication use by 10% to 50%. RELEVANCE TO PATIENT CARE AND CLINICAL PRACTICE: Patient engagement and empowerment successfully convince patients to deprescribe chronic SHs. Quality improvement strategies should also consider interventions directed at prescribers, including education and training, drug utilization reviews, or computer alerts indicating a potentially inappropriate prescription by medication, age, dose, or disease. Educational interventions were effective when they facilitated patient engagement and provided information on the harms and limited evidence supporting chronic use as well as the effectiveness of alternatives. Decision support tools were less effective than prescriber education with patient engagement, although they can be readily incorporated in the workflow through prescribing software.

conclusionsSeveral strategies with demonstrated efficacy in reducing SH use in community practice were identified. Education regarding SH risks, how to taper, and potential alternatives are essential details to provide to clinicians, patients, and families. The strategies presented can guide community healthcare teams toward reducing the community burden of SH use.

Indexed as

DeprescriptionsPhysiciansHumansHypnotics and SedativesInappropriate PrescribingPrimary Health CareHypnotics and Sedativesdeprescribinghypnoticsprescriptionprimary caresedatives

Identifiers

PMID34301151
PMCPMC8899816
OpenAlexW3183816135

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.