Evidence map›Paper›PMID 34301102›Full record

ArticlePolymers2021

N-acylhydrazone Derivative-Loaded Cellulose Acetate Films: Thermoanalytical, Spectroscopic, Mechanical and Morphological Characterization.

Amaro César Lima de Assis, Lívia Maria Coelho de Carvalho Moreira, Beatriz Patrício Rocha, Milena Raissa Bezerra Pereira, Demis Ferreira de Melo, Ricardo Olímpio de Moura, Eduardo Pereira de Azevedo, João Augusto Oshiro-Junior, Bolívar Ponciano Goulart de Lima Damasceno

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Latest advance anti-inflammatory hydrogel wound dressings and traditionalFrontiers in bioengineering and biotechnology · 2024
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Amaro César Lima de AssisGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.
Lívia Maria Coelho de Carvalho MoreiraGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.
Beatriz Patrício RochaGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.ORCID 0000-0002-7144-2944
Milena Raissa Bezerra PereiraGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.
Demis Ferreira de MeloGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.ORCID 0000-0001-8486-5578
Ricardo Olímpio de MouraGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.
Eduardo Pereira de AzevedoGraduate Program of Biotechnology, Laureate International Universities-Universidade Potiguar (UnP), Natal 59056-000, Rio Grande do Norte, Brazil.
João Augusto Oshiro-JuniorGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.ORCID 0000-0001-7247-1598
Bolívar Ponciano Goulart de Lima DamascenoGraduate Program in Pharmaceutical Sciences, Biological and Health Sciences Center, State University of Paraíba (UEPB), Av. Juvêncio Arruda, s/n, Bairro Universitário, Campina Grande 58429-600, Paraíba, Brazil.ORCID 0000-0002-0747-0297
Universidade Estadual da Paraíba · BRUniversidade Potiguar · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001
6 · The paper itself

Abstract

Cellulose acetate (ACT) is one of the most important cellulose derivatives due to its biodegradability and low toxicity, presenting itself as one of the main substitutes for synthetic materials in the development of wound dressing films. The incorporation of a N-acylhydrazonic derivative (JR19), with its promising anti-inflammatory activity, may represent an alternative for the treatment of skin wounds. This work aims to develop and to physicochemically and mechanically characterize ACT films containing JR19. The films were prepared using the 'casting' method and further characterized by thermoanalytical and spectroscopic techniques. In addition, mechanical tests and morphological analysis were performed. Thermogravimetry (TG) and differential scanning calorimetry (DSC) analyses showed that the thermal events attributed to excipients and films were similar, indicating the absence of physical incompatibilities between ACT and JR19. Infrared spectroscopy showed that JR19 was incorporated into ACT films. The characteristic band attributed to C≡N (2279 to 2264 cm

Indexed as

cellulose acetateN-acylhydrazonic derivativepolymeric filmsthermal analysis

Identifiers

PMID34301102
PMCPMC8309645
OpenAlexW3184472280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.