Evidence map›Paper›PMID 34301076›Full record

ReviewPolymers2021

Natural-Based Biomaterial for Skin Wound Healing (Gelatin vs. Collagen): Expert Review.

Ruth Naomi, Hasnah Bahari, Pauzi Muhd Ridzuan, Fezah Othman

Open access · goldAbstract readReview
In one paragraph

Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 189 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  7. Review
  8. ACS omega · 2026
    Article
  9. Article
  10. Review
  11. SiOAdvanced healthcare materials · 2026
    Article
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  13. Article
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  16. Article
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  19. Review
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ruth NaomiDepartment of Human Anatomy, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.ORCID 0000-0002-7937-1255
Hasnah BahariDepartment of Human Anatomy, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.ORCID 0000-0001-8302-4136
Pauzi Muhd RidzuanEstika Research Centre, Kuala Terengganu 21080, Terengganu, Malaysia.
Fezah OthmanDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.ORCID 0000-0002-0924-6264
Universiti Putra Malaysia · MYUniversiti Malaysia Terengganu · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collagen (Col) and gelatin are most extensively used in various fields, particularly in pharmaceuticals and therapeutics. Numerous researchers have proven that they are highly biocompatible to human tissues, exhibit low antigenicity and are easy to degrade. Despite their different sources both Col and gelatin have almost the same effects when it comes to wound healing mechanisms. Considering this, the bioactivity and biological effects of both Col and gelatin have been, and are being, constantly investigated through in vitro and in vivo assays to obtain maximum outcomes in the future. With regard to their proven nutritional values as sources of protein, Col and gelatin products exert various possible biological activities on cells in the extracellular matrix (ECM). In addition, a vast number of novel Col and gelatin applications have been discovered. This review compared Col and gelatin in terms of their structures, sources of derivatives, physicochemical properties, results of in vitro and in vivo studies, their roles in wound healing and the current challenges in wound healing. Thus, this review provides the current insights and the latest discoveries on both Col and gelatin in their wound healing mechanisms.

Indexed as

biomaterials scaffoldscollagengelatinin vitro and in vivophysicochemical propertywound healing

Identifiers

PMID34301076
PMCPMC8309321
OpenAlexW3185677962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.