ReviewPolymers2021
Polyelectrolyte Multilayer Films Based on Natural Polymers: From Fundamentals to Bio-Applications.
Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Decoding Cytoskeletal Mechanobiology with Tunable Microenvironments.ACS biomaterials science & engineering · 2026Article
- Review
- Carboxymethyl kappa-carrageenan polyelectrolyte multilayers: anticoagulant blood-compatible coatings as sustainable alternatives to heparin for blood-contacting surfaces.Research square · 2025Article
- Layer-by-layer assembly: advancing skin repair, one layer at a time.RSC advances · 2025Review
- Transparent Biocompatible Polyelectrolyte Multilayer Coatings on Apples: Formation and Properties.ACS food science & technology · 2025Article
- Spectroscopic investigation of two xanthane dyes and design of a FRET based pesticide sensor.Scientific reports · 2025Article
- Carboxymethyl kappa carrageenan polyelectrolyte multilayers as blood contacting surfaces.Discover biotechnology · 2025Article
- Zero-Order Kinetics Release of Lamivudine from Layer-by-Layer Coated Macromolecular Prodrug Particles.International journal of molecular sciences · 2024Article
- Protein-based layer-by-layer films for biomedical applications.Chemical science · 2024Review
- Acidochromic Free-Standing Multilayered Chitosan-Pyranoflavylium/Alginate Membranes toward Food Smart Packaging Applications.ACS applied polymer materials · 2024Article
- Recent Developments in Layer-by-Layer Assembly for Drug Delivery and Tissue Engineering Applications.Advanced healthcare materials · 2024Review
- Effects of native and particulate polyphenols on DNA damage and cell viability after UV-C exposure.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Antibacterial Films of Silver Nanoparticles Embedded into Carboxymethylcellulose/Chitosan Multilayers on Nanoporous Silicon: A Layer-by-Layer Assembly Approach Comparing Dip and Spin Coating.International journal of molecular sciences · 2023Article
- Synthetic versus Natural Precursor Layer: A Study on the Properties of Biocompatible Chitosan/Carboxymethyl Cellulose Nanofilms.ACS omega · 2023Article
- Polyelectrolyte Coatings-A Viable Approach for Cultural Heritage Protection.Materials (Basel, Switzerland) · 2023Review
- Chitosan-Based Biomaterials: Insights into Chemistry, Properties, Devices, and Their Biomedical Applications.Marine drugs · 2023Review
- Optimization of Multilayer Films Composed of Chitosan and Low-Methoxy Amidated Pectin as Multifunctional Biomaterials for Drug Delivery.International journal of molecular sciences · 2022Article
- Tailored Polyelectrolyte Multilayer Systems by Variation of Polyelectrolyte Composition and EDC/NHS Cross-Linking: Physicochemical Characterization and In Vitro Evaluation.Nanomaterials (Basel, Switzerland) · 2022Article
- The Potential of Polyelectrolyte Multilayer Films as Drug Delivery Materials.International journal of molecular sciences · 2022Review
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Natural polymers are of great interest in the biomedical field due to their intrinsic properties such as biodegradability, biocompatibility, and non-toxicity. Layer-by-layer (LbL) assembly of natural polymers is a versatile, simple, efficient, reproducible, and flexible bottom-up technique for the development of nanostructured materials in a controlled manner. The multiple morphological and structural advantages of LbL compared to traditional coating methods (i.e., precise control over the thickness and compositions at the nanoscale, simplicity, versatility, suitability, and flexibility to coat surfaces with irregular shapes and sizes), make LbL one of the most useful techniques for building up advanced multilayer polymer structures for application in several fields, e.g., biomedicine, energy, and optics. This review article collects the main advances concerning multilayer assembly of natural polymers employing the most used LbL techniques (i.e., dipping, spray, and spin coating) leading to multilayer polymer structures and the influence of several variables (i.e., pH, molar mass, and method of preparation) in this LbL assembly process. Finally, the employment of these multilayer biopolymer films as platforms for tissue engineering, drug delivery, and thermal therapies will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.