Evidence map›Paper›PMID 34300732›Full record

ArticleMaterials (Basel, Switzerland)2021

Qualitative Analysis of Remineralization Capabilities of Bioactive Glass (NovaMin) and Fluoride on Hydroxyapatite (HA) Discs: An In Vitro Study.

Shu-Min Hsu, Muhammad Alsafadi, Christina Vasconez, Chaker Fares, Valentin Craciun, Edgar O'Neill, Fan Ren, Arthur Clark, Josephine Esquivel-Upshaw

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shu-Min HsuDepartment of Restorative Dental Sciences, Division of Prosthodontics, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-0701-0896
Muhammad AlsafadiDepartment of Restorative Dental Sciences, Division of Prosthodontics, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Christina VasconezDepartment of Restorative Dental Sciences, Division of Prosthodontics, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Chaker FaresDepartment of Chemical Engineering, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0001-9596-2381
Valentin CraciunNational Institute for Lasers, Plasma and Radiation Physics, 077125 Magurele, Romania.ORCID 0000-0003-1458-8653
Edgar O'NeillDepartment of Restorative Dental Sciences, Division of Prosthodontics, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Fan RenDepartment of Chemical Engineering, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0001-9234-019X
Arthur ClarkDepartment of Restorative Dental Sciences, Division of Prosthodontics, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Josephine Esquivel-UpshawDepartment of Restorative Dental Sciences, Division of Prosthodontics, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-3642-8087

Funding

Novel coatings to minimize surface degradation and fracture susceptibility of dental ceramicsR01DE025001 · NIDCR · UNIVERSITY OF FLORIDA · PI ESQUIVEL-UPSHAW, JOSEPHINE F. · 2016 to 2020
$4.2M
NIDCR NIH HHS R01 DE025001Romanian NUCLEU LAPLAS VI no. 16N/2019 program project code PN-III-P2-2.1-PED-2019-2949
6 · The paper itself

Abstract

Tooth decay is a prevalent disease that initiates when the oral pH becomes acidic. Fluoride and/or bioactive glass (NovaMin) were used to regenerate/repair teeth that had been decalcified. In this present study, we investigated the effect of fluoride and/or bioactive glass (NovaMin) on remineralization of hydroxyapatite (HA) discs, which mimic the enamel surface of natural teeth. HA discs were etched with phosphoric acid and treated with one of the following toothpastes: (1) Sensodyne toothpaste with fluoride; (2) Sensodyne toothpaste with fluoride and bioactive glass (NovaMin); (3) Tom's toothpaste without fluoride or bioactive glass (NovaMin); and (4) Tom's toothpaste with bioactive glass (NovaMin). The toothpastes were applied on the etched discs for two minutes, once a day for 15 days. Scanning electron microscopy (SEM) was used to analyze surface morphologies and X-ray photoelectron spectroscopy (XPS) was used to analyze surface compositions. Tom's toothpaste with only NovaMin demonstrated the most remineralization potential compared with the other groups. In conclusion, incorporating bioactive glass (NovaMin) into toothpastes could benefit the repair and remineralization of teeth.

Indexed as

bioactive glassdemineralizationdental decayhydroxyapatiteremineralization

Identifiers

PMID34300732
PMCPMC8306171

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.