Evidence map›Paper›PMID 34300421›Full record

ArticleSensors (Basel, Switzerland)2021

Optical Simulation and Experimental Assessment with Time-Walk Correction of TOF-PET Detectors with Multi-Ended Readouts.

Siwei Xie, Zhiliang Zhu, Xi Zhang, Qiangqiang Xie, Hongsen Yu, Yibin Zhang, Jianfeng Xu, Qiyu Peng

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. FPGA-based digitizer for BGO-based time-of-flight PET.Physics in medicine and biology · 2025
    Article
  2. A Time-Walk and Timing-Shift Correction Method for Dual-Ended Readout TOF-DOI PET Detectors.IEEE transactions on radiation and plasma medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siwei XieInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen 518107, China.ORCID 0000-0003-1238-6775
Zhiliang ZhuInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen 518107, China.
Xi ZhangState Key Lab of Digital Manufacturing Equipment & Technology, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan 430070, China.ORCID 0000-0002-4918-0810
Qiangqiang XieState Key Lab of Digital Manufacturing Equipment & Technology, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan 430070, China.ORCID 0000-0003-0980-805X
Hongsen YuState Key Lab of Digital Manufacturing Equipment & Technology, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan 430070, China.
Yibin ZhangInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen 518107, China.
Jianfeng XuState Key Lab of Digital Manufacturing Equipment & Technology, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan 430070, China.
Qiyu PengInstitute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen 518107, China.

Funding

National Natural Science Foundation of China 51627807
6 · The paper itself

Abstract

As a commonly used solution, the multi-ended readout can measure the depth-of-interaction (DOI) for positron emission tomography (PET) detectors. In the present study, the effects of the multi-ended readout design were investigated using the leading-edge discriminator (LED) triggers on the timing performance of time-of-flight (TOF) PET detectors. At the very first, the photon transmission model of the four detectors, namely, single-ended readout, dual-ended readout, side dual-ended readout, and triple-ended readout, was established in Tracepro. The optical simulation revealed that the light output of the multi-ended readout was higher. Meanwhile, the readout circuit could be triggered earlier. Especially, in the triple-ended readout, the light output at 0.5 ns was observed to be nearly twice that of the single-ended readout after the first scintillating photon was generated. Subsequently, a reference detector was applied to test the multi-ended readout detectors that were constructed from a 6 × 6 × 25 mm

Indexed as

Positron-Emission TomographyScintillation CountingAlgorithmsComputer SimulationPhotonscoincidence timing resolutiondual-ended readoutoptical simulationpositron emission tomographytime of flight

Identifiers

PMID34300421
PMCPMC8309550

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.