Evidence map›Paper›PMID 34300352›Full record

ArticleJournal of clinical medicine2021

Nonalcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma: Clinical Patterns, Outcomes, and Prognostic Factors for Overall Survival-A Retrospective Analysis of a Slovak Cohort.

Dominik Safcak, Sylvia Drazilova, Jakub Gazda, Igor Andrasina, Svetlana Adamcova-Selcanova, Radovan Barila, Michal Mego, Marek Rac, Lubomir Skladany, Miroslav Zigrai and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Dominik SafcakDepartment of Radiotherapy and Oncology, East Slovakia Institute of Oncology, Rastislavova 43, 041 91 Kosice, Slovakia.
Sylvia DrazilovaInternal Medicine Department, Hospital Poprad a.s., Banicka 803, 058 01 Poprad, Slovakia.ORCID 0000-0003-2448-6757
Jakub Gazda2nd Department of Internal Medicine, P. J. Safarik University and L. Pasteur University Hospital, Trieda SNP 1, 040 11 Kosice, Slovakia.ORCID 0000-0003-2246-2217
Igor AndrasinaDepartment of Radiotherapy and Oncology, East Slovakia Institute of Oncology, Rastislavova 43, 041 91 Kosice, Slovakia.
Svetlana Adamcova-Selcanova2nd Department of Internal Medicine, HEGITO, F. D. Roosevelt University Hospital, Namestie L Svobodu 1, 975 17 Banska Bystrica, Slovakia.ORCID 0000-0001-8181-1937
Radovan BarilaOncological Cluster, Stefan Kukura Hospital in Michalovce, Spitalska Ulica 2, 071 01 Michalovce, Slovakia.
Michal Mego2nd Department of Oncology, Faculty of Medicine, Comenius University and National Oncology Institute of Slovakia, Klenova 1, 833 10 Bratislava, Slovakia.ORCID 0000-0002-6511-6827
Marek RacDepartment of Internal Medicine, Teaching Hospital Nitra, Spitalska 6, 949 01 Nitra, Slovakia.
Lubomir Skladany2nd Department of Internal Medicine, HEGITO, F. D. Roosevelt University Hospital, Namestie L Svobodu 1, 975 17 Banska Bystrica, Slovakia.ORCID 0000-0001-5171-3623
Miroslav Zigrai1st Department of Internal Medicine, Ladislav Derer University Hospital in Bratislava, Limbova 5, 833 05 Bratislava-Kramare, Slovakia.
Martin Janicko2nd Department of Internal Medicine, P. J. Safarik University and L. Pasteur University Hospital, Trieda SNP 1, 040 11 Kosice, Slovakia.ORCID 0000-0002-3329-3968
Peter Jarcuska2nd Department of Internal Medicine, P. J. Safarik University and L. Pasteur University Hospital, Trieda SNP 1, 040 11 Kosice, Slovakia.
University of Pavol Jozef Šafárik · SKComenius University Bratislava · SKŠtefan Kukura Hospital in Michalovce · SKUniversity Hospital Bratislava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare NAFLD-related HCC and other etiology-related HCC and to describe predictive factors for survival in patients with NAFLD-related HCC independent of the BCLC staging system.

methodsWe performed a multicenter longitudinal retrospective observational study of patients diagnosed with HCC during the period from 2010 through 2016.

results12.59% of patients had NAFLD-related HCC, and 21.91% had either NAFLD or cryptogenic etiology. NAFLD-related HCC patients were younger (

conclusionNAFLD-related HCC patients have a similar prognosis when compared to other etiology-related HCC. In NAFLD-related HCC patients, ALBI and PLR are significant predictors of the overall survival independent of the BCLC staging system.

Indexed as

cirrhosishepatocellular cancernonalcoholic fatty liver diseasenonalcoholic steatohepatitisoverall survivalprognostic factors

Identifiers

PMID34300352
PMCPMC8306860
OpenAlexW3186379977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.