Evidence map›Paper›PMID 34300320›Full record

ReviewJournal of clinical medicine2021

Preeclampsia and Cardiovascular Risk for Offspring.

Wiktor Wojczakowski, Żaneta Kimber-Trojnar, Filip Dziwisz, Magdalena Słodzińska, Hubert Słodziński, Bożena Leszczyńska-Gorzelak

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Hypertensive disorders of pregnancy and offspring's kidney health.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  6. Article
  7. Pregnancy as a Window for Hypertension and Cardiovascular Prevention in Women: A Life-Course Perspective Based on the 2025 ESC Guidelines.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Review
  8. Preeclampsia Screening.Diagnostics (Basel, Switzerland) · 2026
    Review
  9. Article
  10. Deletion of endothelial KLF4 as a model for preeclampsia.bioRxiv : the preprint server for biology · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Endothelial Progenitor Cells in Life, Pregnancy and Disease.Expert reviews in molecular medicine · 2025
    Review
  18. Gut Microbiome and Estrogen.Journal of menopausal medicine · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Wiktor WojczakowskiDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Żaneta Kimber-TrojnarDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0001-7295-0409
Filip DziwiszDepartment of Interventional Cardiology and Cardiac Arrhythmias, Medical University of Lodz, 90-549 Łódź, Poland.
Magdalena SłodzińskaDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Hubert SłodzińskiInstitute of Medical Sciences, State School of Higher Education in Chełm, 22-100 Chełm, Poland.
Bożena Leszczyńska-GorzelakDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Medical University of Lublin · PLMedical University of Lodz · PLState School of Higher Education in Chełm · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is growing evidence of long-term cardiovascular sequelae in children after in utero exposure to preeclampsia. Maternal hypertension and/or placental ischaemia during pregnancy increase the risk of hypertension, stroke, diabetes, and cardiovascular disease (CVD) in the offspring later in life. The mechanisms associated with CVD seem to be a combination of genetic, molecular, and environmental factors which can be defined as fetal and postnatal programming. The aim of this paper is to discuss the relationship between pregnancy complicated by preeclampsia and possibility of CVD in the offspring. Unfortunately, due to its multifactorial nature, a clear dependency mechanism between preeclampsia and CVD is difficult to establish.

Indexed as

cardiovascular riskfetal programminggestational hypertensionoffspringpreeclampsia

Identifiers

PMID34300320
PMCPMC8306208
OpenAlexW3184037307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.