Evidence map›Paper›PMID 34300317›Full record

ArticleJournal of clinical medicine2021

The Influence of Depression, Anxiety and Cognition on the Treatment Effects of

Petra Brüggemann, Marília Grando Sória, Juliette Brandes-Schramm, Birgit Mazurek

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Journal of clinical medicine · 2025
    Article
  2. Article
  3. Article
  4. Frontiers in neurology · 2024
    Article
  5. Article
  6. Migrainous Vertigo, Tinnitus, and Ear Symptoms and Alternatives.Otolaryngologic clinics of North America · 2022
    Review
  7. Review
  8. Frontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Petra BrüggemannTinnitus Center, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Marília Grando SóriaMedical Scientific Services, Dr. Willmar Schwabe GmbH & Co. KG, 76227 Karlsruhe, Germany.
Juliette Brandes-SchrammMedical Scientific Services, Dr. Willmar Schwabe GmbH & Co. KG, 76227 Karlsruhe, Germany.ORCID 0000-0001-8182-2572
Birgit MazurekTinnitus Center, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-9587-6632
Charité - Universitätsmedizin Berlin · DEDr Willmar Schwabe (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComorbid occurrence of tinnitus and emotional symptoms of anxiety and depression is highly prevalent. The

methodsWe performed a mediation analysis to evaluate direct effects of EGb 761

resultsIn total, 594 patients suffered from tinnitus (EGb 761

conclusionsEGb 761

Indexed as

anxietydementiadepressionEGb 761Ginkgo bilobamediation analysistinnitus

Identifiers

PMID34300317
PMCPMC8307082
OpenAlexW3185047092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.