ReviewJournal of clinical medicine2021
Platelet and Thrombophilia-Related Risk Factors of Retinal Vein Occlusion.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Associations between psychiatric disorders and medication use, and retinal occlusion: a large-scale retrospective cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Hypertension, Deep Retinal Perfusion, and Concurrent Visual Acuity in Retinal Vein Occlusion: A Cross-Sectional OCTA Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Serum Lipid Profile, Atherogenic Indices, and Systemic Inflammatory Markers in Retinal Vein Occlusion: A Retrospective Case-Control Study.Journal of ophthalmology · 2026Article
- Recent advances in the treatment of retinal vein occlusion with traditional Chinese medicine.International ophthalmology · 2025Review
- Detection of Retinal and Choriocapillaris Microvascular Changes in Retinal Vein Occlusion and Fellow Eyes by Optical Coherence Tomography Angiography: A Systematic Review and Meta-Analysis.Ophthalmology and therapy · 2025Article
- The Diagnosis and Treatment of Branch Retinal Vein Occlusions: An Update.Biomedicines · 2025Review
- Exploring potential imaging biomarkers for ischemic retinal vein occlusion: insights from fundus autofluorescence and optical coherence tomography.Frontiers in medicine · 2025Article
- Is retinal vein occlusion highly associated with an increased risk of myocardial infarction? A systematic review and meta-analysis.International journal of retina and vitreous · 2024Review
- Concurrent Onset of Central Retinal Vein Occlusion and Inflammation of a Large Maxillary Odontogenic Cyst: Case Report and Analysis.Reports (MDPI) · 2024Article
- Relation between peripheral blood inflammatory indices and severity of central retinal artery occlusion.PeerJ · 2024Article
- Case reports: Intraoperative migratory retinal venous thrombus in proliferative diabetic retinopathy.Frontiers in medicine · 2024Article
- Evaluation of Central and Peripheral Retinal Vascular Changes in the Fellow Eyes of Patients with Unilateral Retinal Vein OcclusionsTurkish journal of ophthalmology · 2023Article
- High prevalence of thrombophilic risk factors in patients with central retinal artery occlusion.Thrombosis journal · 2023Article
- Red Blood Cells: A Newly Described Partner in Central Retinal Vein Occlusion Pathophysiology?International journal of molecular sciences · 2023Review
- The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term.Journal of clinical laboratory analysis · 2022Article
- Platelet-Derived Procoagulant Microvesicles Are Elevated in Patients with Retinal Vein Occlusion (RVO).Journal of clinical medicine · 2022Article
- Vitamin B12 levels in patients with retinal vein occlusion and their relation with clinical outcome: a retrospective study.Internal and emergency medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Retinal vein occlusion (RVO) is a heterogenous disorder in which the formation of a thrombus results in the retinal venous system narrowing and obstructing venous return from the retinal circulation. The pathogenesis of RVO remains uncertain, but it is believed to be multifactorial and to depend on both local and systemic factors, which can be divided into vascular, platelet, and hypercoagulable factors. The vascular factors include dyslipidaemia, high blood pressure, and diabetes mellitus. Regarding the platelet factors, platelet function, mean platelet volume (MPV), platelet distribution width (PDW), and platelet large cell ratio (PLCR) play key roles in the diagnosis of retinal vein occlusion and should be monitored. Nevertheless, the role of a hypercoagulable state in retinal vein occlusion remains unclear and requires further studies. Therefore, the following article will present the risk factors of RVO associated with coagulation disorders, as well as the acquired and genetic risk factors of thrombophilia. According to Virchow's triad, all factors mentioned above lead to thrombus formation, which causes pathophysiological changes inside venous vessels in the fundus of the eye, which in turn results in the vessel occlusion. Therefore, a diagnosis of retinal vein occlusion should be based on both eye examination and general examination, including laboratory tests.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.