Evidence map›Paper›PMID 34300229›Full record

ArticleJournal of clinical medicine2021

Modified Technique for Wirsung-Pancreatogastric Anastomosis after Pancreatoduodenectomy: A Single Center Experience and Systematic Review of the Literature.

Cinzia Bizzoca, Salvatore Fedele, Anna Stella Lippolis, Fabrizio Aquilino, Marco Castellana, Maria Raffaella Basile, Giuseppe Lucarelli, Leonardo Vincenti

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Cinzia BizzocaDepartment of General Surgery "Ospedaliera", Polyclinic Hospital of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.ORCID 0000-0003-0410-0490
Salvatore FedeleGeneral Surgery Unit, National Institute of Gastroenterology Saverio de Bellis, Research Hospital, via Turi 27, Castellana Grotte, 70013 Bari, Italy.
Anna Stella LippolisDepartment of General Surgery, San Paolo Hospital, via Capo Scardicchio, 70123 Bari, Italy.ORCID 0000-0002-9482-8575
Fabrizio AquilinoGeneral Surgery Unit, National Institute of Gastroenterology Saverio de Bellis, Research Hospital, via Turi 27, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0003-1787-3791
Marco CastellanaUnit of Research Methodology and Data Sciences for Population Health, National Institute of Gastroenterology Saverio de Bellis, Research Hospital, via Turi 27, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-1175-8998
Maria Raffaella BasileDepartment of General Surgery, San Paolo Hospital, via Capo Scardicchio, 70123 Bari, Italy.
Giuseppe LucarelliAndrology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation-Urology, University of Bari, 70124 Bari, Italy.ORCID 0000-0001-7807-1229
Leonardo VincentiDepartment of General Surgery "Ospedaliera", Polyclinic Hospital of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Gastroenterology Hospital "Saverio de Bellis" · ITAzienda Universitaria Ospedaliera Consorziale - Policlinico Bari · ITOspedale San Paolo · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe mortality rate following pancreaticoduodenectomy (PD) has been decreasing over the past few years; nonetheless, the morbidity rate remains elevated. The most common complications after PD are post-operative pancreatic fistula (POPF) and delayed gastric emptying (DGE) syndrome. The issue as to which is the best reconstruction method for the treatment of the pancreatic remnant after PD is still a matter of debate. The aim of this study was to retrospectively analyze the morbidity rate in 100 consecutive PD reconstructed with Wirsung-Pancreato-Gastro-Anastomosis (WPGA), performed by a single surgeon applying a personal modification of the pancreatic reconstruction technique.

methodsDuring an 8-year period (May 2012 to March 2020), 100 consecutive patients underwent PD reconstructed with WPGA. The series included 57 males and 43 females (M/F 1.32), with a mean age of 68 (range 41-86) years. The 90-day morbidity and mortality were retrospectively analyzed. Additionally, a systematic review was conducted, comparing our technique with the existing literature on the topic.

resultsWe observed eight cases of clinically relevant POPF (8%), three cases of "primary" DGE (3%) and four patients suffering "secondary" DGE. The surgical morbidity and mortality rate were 26% and 6%, respectively. The median hospital stay was 13.6 days. The systematic review of the literature confirmed the originality of our modified technique for Wirsung-Pancreato-Gastro-Anastomosis.

conclusionsOur modified double-layer WPGA is associated with a very low incidence of POPF and DGE. Also, the technique avoids the risk of acute hemorrhage of the pancreatic parenchyma.

Indexed as

pancreatic cancerpancreaticoduodenectomypancreatic surgerywirsung-pancreatogastric anastomosis

Identifiers

PMID34300229
PMCPMC8303560
OpenAlexW3177695055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.