Evidence map›Paper›PMID 34300202›Full record

ArticleJournal of clinical medicine2021

Pre-Stroke Statin Therapy Improves In-Hospital Prognosis Following Acute Ischemic Stroke Associated with Well-Controlled Nonvalvular Atrial Fibrillation.

Paweł Wańkowicz, Jacek Staszewski, Aleksander Dębiec, Marta Nowakowska-Kotas, Aleksandra Szylińska, Agnieszka Turoń-Skrzypińska, Iwona Rotter

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Early Occupational Therapy Intervention in the Hospital Discharge after Stroke.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Paweł WańkowiczDepartment of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 48, 71-210 Szczecin, Poland.ORCID 0000-0001-7956-1107
Jacek StaszewskiDepartment of Neurology, Military Medical Institute, Szaserów 128, 04-141 Warszawa, Poland.ORCID 0000-0002-5588-9148
Aleksander DębiecDepartment of Neurology, Military Medical Institute, Szaserów 128, 04-141 Warszawa, Poland.ORCID 0000-0002-0780-3186
Marta Nowakowska-KotasDepartment of Neurology, Medical University of Wrocław, Borowska 213, 50-566 Wrocław, Poland.ORCID 0000-0002-3173-8337
Aleksandra SzylińskaDepartment of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 48, 71-210 Szczecin, Poland.ORCID 0000-0001-6105-5329
Agnieszka Turoń-SkrzypińskaDepartment of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 48, 71-210 Szczecin, Poland.ORCID 0000-0002-4140-4656
Iwona RotterDepartment of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 48, 71-210 Szczecin, Poland.ORCID 0000-0002-4337-6476
Pomeranian Medical University · PLWojskowy Instytut Medycyny Lotniczej · PLUniversity of Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many studies have confirmed the positive effect of statins in the secondary prevention of ischemic stroke. Although several studies have concluded that statins may also be beneficial in patients with atrial fibrillation-related stroke, the results of those studies are inconclusive. Therefore, the aim of this study was to analyze the effect of pre-stroke statin therapy on atrial fibrillation-related stroke among patients with a well-controlled atrial fibrillation. This retrospective multicenter analysis comprised 2309 patients with acute stroke, with a total of 533 patients meeting the inclusion criteria. The results showed a significantly lower neurological deficit on the National Institutes of Health Stroke Scale at hospital admission and discharge in the group of atrial fibrillation-related stroke patients who took statins before hospitalization compared with those who did not (

Indexed as

atrial fibrillationischemic strokemortalityNOACoutcomestatinVKA

Identifiers

PMID34300202
PMCPMC8305559
OpenAlexW3181793045

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.