Evidence map›Paper›PMID 34300198›Full record

ArticleJournal of clinical medicine2021

A Risk Score for Predicting Long-Term Mortality Following Off-Pump Coronary Artery Bypass Grafting.

Tomasz Kamil Urbanowicz, Michał Michalak, Aleksandra Gąsecka, Anna Olasińska-Wiśniewska, Bartłomiej Perek, Michał Rodzki, Michał Bociański, Marek Jemielity

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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  14. Dyslipidemia in Transplant Patients: Which Therapy?Journal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tomasz Kamil UrbanowiczDepartment of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0001-8080-2764
Michał MichalakDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-2852-3984
Aleksandra Gąsecka1st Chair and Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0001-5083-7587
Anna Olasińska-WiśniewskaDepartment of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Bartłomiej PerekDepartment of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0003-2398-9571
Michał RodzkiDepartment of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0003-1057-8044
Michał BociańskiDepartment of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Marek JemielityDepartment of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Poznan University of Medical Sciences · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOff-pump coronary artery bypass grafting (OPCAB) comprises 15-30% of all bypass grafting surgeries. The currently available perioperative scores such as Euroscore and STS score do not specifically predict long-term mortality after off-pump procedures. The neutrophil-to-lymphocyte ratio (NLR) is one of the new, easily accessible markers of inflammation with proven predictive value in cardiovascular diseases. We aimed to develop the first risk score for long-term mortality after OPCAB and to determine if the perioperative value of NLR predicts long-term mortality in OPCAB patients.

methodsIn total, 440 consecutive patients with multivessel stable coronary artery disease undergoing OPCAB were recruited. Differential leukocyte counts were obtained by a routine hematology analyzer. Data regarding mortality during a median follow-up time of 5.3 years were obtained from the Polish National Health Service database. An independent population of 242 patients served as a validation cohort.

resultsAll-cause mortality was influenced by different clinical risk factors. In multivariate regression analysis, chronic obstructive pulmonary disease, stroke history, post-operative NLR and LVEF were independent predictors of mortality. Combing all independent predictors predicted long-term all-cause mortality with 68.5% sensitivity and 71.5% specificity (AUC = 0.704,

conclusionsWe developed and validated the first simplified risk score to predict mortality following OPCAB based on easily accessible clinical factors. This risk score can be used when obtaining a patient's informed consent and as an aid in determining treatment.

Indexed as

coronary artery bypass graftinglong-term mortalitymultivessel coronary artery diseaseneutrophil-to-lymphocyte ratiooff-pumppredictionrisk stratification

Identifiers

PMID34300198
PMCPMC8305554
OpenAlexW3181131584

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.