Evidence map›Paper›PMID 34300163›Full record

ArticleInternational journal of environmental research and public health2021

Inactivation of Replication-Competent Vesicular Stomatitis Virus as SARS-CoV-2 Surrogate on Common Surfaces by Disinfectants.

Zachary C Pope, Timothy J Kottke, Aditya Shah, Richard G Vile, Stacey A Rizza

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zachary C PopeWell Living Lab, Rochester, MN 55902, USA.
Timothy J KottkeDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Aditya ShahDivision of Infectious Diseases, Mayo Clinic, Rochester, MN 55905, USA.
Richard G VileDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Stacey A RizzaDivision of Infectious Diseases, Mayo Clinic, Rochester, MN 55905, USA.
Mayo Clinic in Florida · USMayo Clinic in Arizona · US

Funding

Delos Living, LLC. N/A; Internal Grant
6 · The paper itself

Abstract

Surface disinfection is part of a larger mitigation strategy to prevent the spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus causing coronavirus disease-2019 (COVID-19). Research evaluating the time, nature, and extent of surface disinfection of replication-competent viruses is needed. We evaluated the efficacy of two disinfectants against a replication-competent SARS-CoV-2 surrogate on three common public surfaces. Vesicular stomatitis virus expressing green fluorescent protein (VSV-GFP) was our replication-competent SARS-CoV-2 surrogate. Disinfection occurred using Super Sani-Cloth Germicidal Disposable Wipes and Oxivir Tb spray per manufacturer instructions to test the efficacy at reducing the presence, viability, and later replication of VSV-GFP on stainless steel, laminate wood, and porcelain surfaces using standardized methods after recovery and toxicity testing. During the main trials, we placed 100 µL spots of VSV-GFP at viral titers of 10

Indexed as

COVID-19DisinfectantsVesicular StomatitisAnimalsHumansSARS-CoV-2Vesicular stomatitis Indiana virusDisinfectantsCOVID-19disinfectioninfection controlinfectious diseasesvirology

Identifiers

PMID34300163
PMCPMC8304672
OpenAlexW3186263718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.