Evidence map›Paper›PMID 34299864›Full record

ArticleInternational journal of environmental research and public health2021

Estimating an EQ-5D-3L Value Set for Romania Using Time Trade-Off.

Marian Sorin Paveliu, Elena Olariu, Raluca Caplescu, Yemi Oluboyede, Ileana-Gabriela Niculescu-Aron, Simona Ernu, Luke Vale

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Revisiting health state preferences after 20 years: A new EQ-5D-3L value set for the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  2. A Head-On Comparison of EQ-VT- and Crosswalk-Based EQ-5D-5L Value Sets.Applied health economics and health policy · 2025
    Article
  3. Valuation of the EQ-5D-3L in Jordan.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  4. The EORTC QLU-C10D is a valid cancer-specific preference-based measure for cost-utility and health technology assessment in the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Article
  5. Population norms for the EQ-5D-3L and EQ-5D-5L in Romania.Health and quality of life outcomes · 2023
    Article
  6. EQ-5D-5L: a value set for Romania.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Marian Sorin PaveliuRomanian Academic Society, 020071 Bucharest, Romania.ORCID 0000-0002-0702-1715
Elena OlariuPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK.
Raluca CaplescuDepartment of Statistics and Econometrics, Bucharest University of Economic Studies, 010374 Bucharest, Romania.
Yemi OluboyedePopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK.
Ileana-Gabriela Niculescu-AronDepartment of Statistics and Econometrics, Bucharest University of Economic Studies, 010374 Bucharest, Romania.ORCID 0000-0003-2902-1641
Simona ErnuRomanian Academic Society, 020071 Bucharest, Romania.
Luke ValePopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK.
Newcastle University · GBBucharest University of Economic Studies · RORomanian Society of Nephrology · ROTitu Maiorescu University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide health-related quality of life (HRQoL) data to support health technology assessment (HTA) and reimbursement decisions in Romania, by developing a country-specific value set for the EQ-5D-3L questionnaire.

methodsWe used the cTTO method to elicit health state values using a computer-assisted personal interviewing approach. Interviews were standardized following the most recent version of the EQ-VT protocol developed by the EuroQoL Foundation. Thirty EQ-5D-3L health states were randomly assigned to respondents in blocks of three. Econometric modeling was used to estimate values for all 243 states described by the EQ-5D-3L.

resultsData from 1556 non-institutionalized adults aged 18 years and older, selected from a national representative sample, were used to build the value set. All tested models were logically consistent; the final model chosen to generate the value set was an interval regression model. The predicted EQ-5D-3L values ranged from 0.969 to 0.399, and the relative importance of EQ-5D-3L dimensions was in the following order: mobility, pain/discomfort, self-care, anxiety/depression, and usual activities.

conclusionsThese results can support reimbursement decisions and allow regional cross-country comparisons between health technologies. This study lays a stepping stone in the development of a health technology assessment process more driven by locally relevant data in Romania.

Indexed as

Health StatusQuality of LifeAdultEthnicityHumansRomaniaSurveys and Questionnairescost-utility analysisEQ-5Dhealth-related quality of lifequality-adjusted life yearstime trade-offutilities

Identifiers

PMID34299864
PMCPMC8306594
OpenAlexW3181326094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.