Evidence map›Paper›PMID 34299820›Full record

ReviewInternational journal of environmental research and public health2021

Mandibular Brown Tumor as a Result of Secondary Hyperparathyroidism: A Case Report with 5 Years Follow-Up and Review of the Literature.

Veronika Shavlokhova, Benjamin Goeppert, Matthias M Gaida, Babak Saravi, Frederic Weichel, Andreas Vollmer, Michael Vollmer, Christian Freudlsperger, Christian Mertens, Jürgen Hoffmann

Abstract readCase ReportsReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. [Brown tumor due to hyperparathyroidism secondary to chronic kidney disease: A clinical case].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  3. Brown tumor in the pterygopalatine fossa with maxillary and sphenoidal involvement: a rare case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Brown tumors: Retrospective analysis of 26 cases.Archives of orthopaedic and trauma surgery · 2024
    Article
  11. Article
  12. Review
  13. Massive brown tumors of the jaw: A case report.SAGE open medical case reports · 2023
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Veronika ShavlokhovaDepartment of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Benjamin GoeppertInstitute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Matthias M GaidaInstitute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Babak SaraviDepartment of Orthopedics and Trauma Surgery, Medical Centre-Albert-Ludwigs-University of Freiburg, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0003-2298-3696
Frederic WeichelDepartment of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-0222-7060
Andreas VollmerDepartment of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Michael VollmerDepartment of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Christian FreudlspergerDepartment of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-4289-0457
Christian MertensDepartment of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-6305-364X
Jürgen HoffmannDepartment of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-1322-755X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrown tumor is a rare skeletal manifestation of secondary hyperparathyroidism. Although diagnosis of the disease is increasingly seen in early stages due to improved screening techniques, some patients still present in a progressed disease stage. The treatment depends on tumor mass and varies from a conservative approach with supportive parathyroidectomy to extensive surgical resection with subsequent reconstruction. CASE PRESENTATION: We report a case of extensive mandibular brown tumor in a patient with a history of systemic lupus erythematosus, chronic kidney disease, and secondary hyperparathyroidism. Following radical resection of the affected bone, reconstruction could be successfully performed using a free flap.

conclusionsThere were no signs of recurrence during five years of close follow-up. Increased awareness and multidisciplinary follow-ups could allow early diagnosis and prevent the need for radical therapeutical approaches.

Indexed as

Hyperparathyroidism, SecondaryOsteitis Fibrosa CysticaFollow-Up StudiesHumansMandibleParathyroidectomybrown tumorjawmicrovascular reconstructionradical resectionsecondary hyperparathyroidism

Identifiers

PMID34299820
PMCPMC8304219

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.