Evidence map›Paper›PMID 34299652›Full record

ArticleMolecules (Basel, Switzerland)2021

Development of Chitosan-Based Surfaces to Prevent Single- and Dual-Species Biofilms of

Marta Lima, Rita Teixeira-Santos, Luciana C Gomes, Sara I Faria, Jesus Valcarcel, José Antonio Vázquez, Miguel A Cerqueira, Lorenzo Pastrana, Ana I Bourbon, Filipe J Mergulhão

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Tailoring Polymeric Scaffolds withMolecules (Basel, Switzerland) · 2025
    Article
  2. Article
  3. DisarmingPathogens (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Performance of Graphene/Polydimethylsiloxane Surfaces againstNanomaterials (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Using Lactobacilli to FightAntibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Marta LimaLEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
Rita Teixeira-SantosLEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.ORCID 0000-0001-7546-9362
Luciana C GomesLEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.ORCID 0000-0002-8992-1097
Sara I FariaLEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
Jesus ValcarcelGrupo de Reciclado y Valorización de Materiales Residuales (REVAL), Instituto de Investigaciones Marinas (IIM-CSIC), C/Eduardo Cabello, 6, CP36208 Vigo, Galicia, Spain.ORCID 0000-0001-7336-4049
José Antonio VázquezGrupo de Reciclado y Valorización de Materiales Residuales (REVAL), Instituto de Investigaciones Marinas (IIM-CSIC), C/Eduardo Cabello, 6, CP36208 Vigo, Galicia, Spain.ORCID 0000-0002-1122-4726
Miguel A CerqueiraInternational Iberian Nanotechnology Laboratory, Department of Life Sciences, Av. Mestre José Veiga s/n, 4715-330 Braga, Portugal.ORCID 0000-0001-6614-3942
Lorenzo PastranaInternational Iberian Nanotechnology Laboratory, Department of Life Sciences, Av. Mestre José Veiga s/n, 4715-330 Braga, Portugal.ORCID 0000-0002-6637-3462
Ana I BourbonInternational Iberian Nanotechnology Laboratory, Department of Life Sciences, Av. Mestre José Veiga s/n, 4715-330 Braga, Portugal.
Filipe J MergulhãoLEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.ORCID 0000-0001-5233-1037
Universidade do Porto · PTInternational Iberian Nanotechnology Laboratory · PTInstituto de Investigacións Mariñas · ES

Funding

Base Funding of the Laboratory for Process Engineering, Environment, Biotechnology and Energy (LEPABE) funded by national funds through the FCT/MCTES (PID-DAC) UIDB/00511/2020CVMAR+I-Industrial Innovation and Marine Biotechnology Valorization project funded by INTERREG V Espanha Portugal (POCTEP) 0302_CVMAR_I_1_PSurfSAFE project funded by the European Union's Horizon 2020 research and innovation programme No 952471Xunta de Galicia by Xunta de Galicia IN607B 2018/2019
6 · The paper itself

Abstract

Implantable medical devices (IMDs) are susceptible to microbial adhesion and biofilm formation, which lead to several clinical complications, including the occurrence of implant-associated infections. Polylactic acid (PLA) and its composites are currently used for the construction of IMDs. In addition, chitosan (CS) is a natural polymer that has been widely used in the medical field due to its antimicrobial and antibiofilm properties, which can be dependent on molecular weight (Mw). The present study aims to evaluate the performance of CS-based surfaces of different Mw to inhibit bacterial biofilm formation. For this purpose, CS-based surfaces were produced by dip-coating and the presence of CS and its derivatives onto PLA films, as well surface homogeneity were confirmed by contact angle measurements, Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The antimicrobial activity of the functionalized surfaces was evaluated against single- and dual-species biofilms of

Indexed as

ChitosanBiofilmsImplants, ExperimentalPseudomonas aeruginosaStaphylococcus aureusSurface PropertiesChitosanantibiofilm activitychitosanchitosan-polylactic acid surfacesdual-species biofilmsimplantable medical devicespolylactic acid surfacesPseudomonas aeruginosasingle-species biofilmsStaphylococcus aureus

Identifiers

PMID34299652
PMCPMC8306285
OpenAlexW3183356343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.