Bio-Guided Fractionation of Stem Bark Extracts from

Marina Naldi, Gloria Brusotti, Gabriella Massolini, Vincenza Andrisano, Caterina Temporini, Manuela Bartolini

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Bio-guided fractionation of (9Z )-5,8,11-trihydroxyoctadec-9-enoic acid from Abelmoschus sagittifolius root as a potent α-glucosidase inhibitor: An integrated in vitro and in silico study.Journal of the science of food and agriculture · 2026
Article
Untargeted Metabolomics Combined with Solid Phase Fractionation for Systematic Characterization of Bioactive Compounds in Hemp with Methane Mitigation Potential.Metabolites · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marina NaldiDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.ORCID 0000-0003-4468-2974

Gloria BrusottiDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-7786-3769

Gabriella MassoliniDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

Vincenza AndrisanoDepartment for Life Quality Studies, Alma Mater Studiorum University of Bologna, Corso D'Augusto 237, 47921 Rimini, Italy.

Caterina TemporiniDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

Manuela BartoliniDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.ORCID 0000-0002-2890-3856

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca no code

6 · The paper itself

Abstract

A combination of flash chromatography, solid phase extraction, high-performance liquid chromatography, and in vitro bioassays was used to isolate phytocomponents endowed with anticholinesterase activity in extract from

Indexed as

AcetylcholinesteraseCholinesterase InhibitorsMolecular Docking SimulationButyrylcholinesteraseGPI-Linked ProteinsHumansMolecular StructurePhyllanthusPlant BarkPlant ExtractsAcetylcholinesteraseACHE protein, humanBCHE protein, humanButyrylcholinesteraseCholinesterase InhibitorsGPI-Linked ProteinsPlant Extractsanti-amyloid propertiesanticholinesterase activitybioassay-guided fractionationPhyllanthus muellarianus

Identifiers

PMID34299650

DOI10.3390/molecules26144376

PMCPMC8307647

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.