Evidence map›Paper›PMID 34299577›Full record

ArticleMolecules (Basel, Switzerland)2021

Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives.

Xiao-Long Sun, Mei-Lin Zhu, Yi-Qun Dai, Hong-Mei Li, Bo-Han Li, Hui Ma, Chang-Hao Zhang, Cheng-Zhu Wu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao-Long SunSchool of Pharmacy, Bengbu Medical College, 2600 Donghai Road, Bengbu 233030, China.
Mei-Lin ZhuSchool of Pharmacy, Bengbu Medical College, 2600 Donghai Road, Bengbu 233030, China.
Yi-Qun DaiSchool of Pharmacy, Bengbu Medical College, 2600 Donghai Road, Bengbu 233030, China.
Hong-Mei LiSchool of Pharmacy, Bengbu Medical College, 2600 Donghai Road, Bengbu 233030, China.
Bo-Han LiSchool of Pharmacy, Bengbu Medical College, 2600 Donghai Road, Bengbu 233030, China.
Hui MaSchool of Pharmacy, Bengbu Medical College, 2600 Donghai Road, Bengbu 233030, China.
Chang-Hao ZhangKey Laboratory of Natural Medicines of the Changbai Mountain, College of Pharmacy, Yanbian University, Ministry of Education, 977 Gongyuan Road, Yanji 133002, China.
Cheng-Zhu WuSchool of Pharmacy, Bengbu Medical College, 2600 Donghai Road, Bengbu 233030, China.

Funding

512 Talent Cultivation Plan of Bengbu Medical College by51202202Education Department of Anhui Natural Science Research Project China KJ2018A0232Natural Science Foundation of Anhui Province 2008085MH284
6 · The paper itself

Abstract

Magnolol (MAG), a biphenolic neolignan, has various biological activities including antitumor effects. In this study, 15 MAG derivatives were semi-synthesized and evaluated for their in vitro anticancer activities. From these derivatives, compound

Indexed as

Antineoplastic AgentsBiphenyl CompoundsCell Line, TumorCell MovementCell ProliferationDrug Screening Assays, AntitumorFemaleHumansLignansNeoplasm InvasivenessTriple Negative Breast NeoplasmsAntineoplastic AgentsBiphenyl CompoundsLignansmagnololcytotoxicityinvasionmagnololmigrationsemi-synthesis

Identifiers

PMID34299577
PMCPMC8303457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.