Evidence map›Paper›PMID 34299549›Full record

ArticleMolecules (Basel, Switzerland)2021

Electrophilically Activated Nitroalkanes in Synthesis of 3,4-Dihydroquinozalines.

Alexander V Aksenov, Igor Yu Grishin, Nicolai A Aksenov, Vladimir V Malyuga, Dmitrii A Aksenov, Mezvah A Nobi, Michael Rubin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alexander V AksenovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.ORCID 0000-0002-6644-9949
Igor Yu GrishinDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.ORCID 0000-0003-4261-824X
Nicolai A AksenovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Vladimir V MalyugaDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Dmitrii A AksenovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Mezvah A NobiDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Michael RubinDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
North-Caucasus Federal University · RUUniversity of Kansas · US

Funding

Ministry of Education and Science of the Russian Federation 0795-2020- 0031Russian Foundation for Basic Research 19-03-00308aRussian Foundation for Basic Research 20-33-90027
6 · The paper itself

Abstract

Nitroalkanes activated with polyphosphoric acid serve as efficient electrophiles in reactions with various nucleophilic amines. Strategically placed second functionality allows for the design of annulation reactions enabling preparation of various heterocycles. This strategy was employed to develop an innovative synthetic approach towards 3,4-dihydroquinazolines from readily available 2-(aminomethyl)anilines.

Indexed as

annulationheterocyclic compoundsnitroalkanesquinozalines

Identifiers

PMID34299549
PMCPMC8306411
OpenAlexW3186659244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.