Evidence map›Paper›PMID 34299517›Full record

ArticleMolecules (Basel, Switzerland)2021

Functional Characterization of Porcine NK-Lysin: A Novel Immunomodulator That Regulates Intestinal Inflammatory Response.

Qian Lin, Qingqing Fu, Daiwen Chen, Bing Yu, Yuheng Luo, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Review
  6. A novel antimicrobial peptide screened by aFrontiers in immunology · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Qian LinInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Qingqing FuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Daiwen ChenInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Bing YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0001-6605-6742
Yuheng LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Zhiqing HuangInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Ping ZhengInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Xiangbing MaoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-6292-7747
Jie YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Junqiu LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Hui YanInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Jun HeInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-1963-9766
Sichuan Agricultural University · CN

Funding

the Development program of Sichuan Province 2018NZDZX0005the National Natural Science Foundation of China 31972599the Youth Innovation teams of animal Feed Biotechnology of Sichuan Province 2016TD0028
6 · The paper itself

Abstract

Porcine NK-Lysine (PNKL) is a new antimicrobial peptide (AMP) identified in the small intestine. In this study, PNKL protein was obtained through heterologous expression in

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaCell LineImmunologic FactorsInflammationIntestinal MucosaModels, MolecularPore Forming Cytotoxic ProteinsProteolipidsRecombinant ProteinsSwineAnti-Bacterial AgentsImmunologic FactorsNK-lysinPore Forming Cytotoxic ProteinsProteolipidsRecombinant Proteinsantimicrobial peptidehemolytic activityMICPorcine NK-Lysin

Identifiers

PMID34299517
PMCPMC8307250
OpenAlexW3181043209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.