Evidence map›Paper›PMID 34299465›Full record

ArticleMolecules (Basel, Switzerland)2021

The Lysozyme Inhibitor Thionine Acetate Is Also an Inhibitor of the Soluble Lytic Transglycosylase Slt35 from

Aysha B Mezoughi, Chiara M Costanzo, Gregor M Parker, Enas M Behiry, Alan Scott, Andrew C Wood, Sarah E Adams, Richard B Sessions, E Joel Loveridge

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aysha B MezoughiSchool of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.ORCID 0000-0001-9641-3026
Chiara M CostanzoDepartment of Chemistry, Swansea University, Singleton Park, Swansea SA2 8PP, UK.
Gregor M ParkerSchool of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.
Enas M BehirySchool of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.
Alan ScottSchool of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.
Andrew C WoodSchool of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.
Sarah E AdamsSchool of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.
Richard B SessionsSchool of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, UK.
E Joel LoveridgeSchool of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/L01758X/1Libyan Embassy PhD studentship 10007Life Sciences Research Network Wales NRNRG4Mar039Royal Society of Chemistry Undergraduate Research Bursary
6 · The paper itself

Abstract

Lytic transglycosylases such as Slt35 from

Indexed as

AcetatesAmino Acid SequenceBacterial ProteinsBinding SitesCatalytic DomainCell WallCrystallography, X-RayEscherichia coliEscherichia coli ProteinsGlycosyltransferasesModels, MolecularMolecular Docking SimulationMuramidasePeptidoglycanPhenothiazinesProtein ConformationAcetatesBacterial ProteinsEscherichia coli ProteinsGlycosyltransferasesMuramidasemurein transglycosylasePeptidoglycanPhenothiazinesthionineantibacterialenzyme inhibitionlytic transglycosylasethionine acetate

Identifiers

PMID34299465
PMCPMC8307938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.