Evidence map›Paper›PMID 34299416›Full record

ReviewMolecules (Basel, Switzerland)2021

Solid-State NMR Spectroscopy: A Key Tool to Unravel the Supramolecular Structure of Drug Delivery Systems.

Marianna Porcino, Xue Li, Ruxandra Gref, Charlotte Martineau-Corcos

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marianna PorcinoCEMHTI UPR CNRS 3079, Université d'Orléans, 45071 Orléans, France.
Xue LiInstitut des Sciences Moléculaires d'Orsay, UMR CNRS 8214, Paris-Sud University, Université Paris Saclay, 91400 Orsay, France.
Ruxandra GrefInstitut des Sciences Moléculaires d'Orsay, UMR CNRS 8214, Paris-Sud University, Université Paris Saclay, 91400 Orsay, France.ORCID 0000-0002-7869-0908
Charlotte Martineau-CorcosCortecNet, 7 Avenue du Hoggar, 91940 Les Ulis, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past decades, nanosized drug delivery systems (DDS) have been extensively developed and studied as a promising way to improve the performance of a drug and reduce its undesirable side effects. DDSs are usually very complex supramolecular assemblies made of a core that contains the active substance(s) and ensures a controlled release, which is surrounded by a corona that stabilizes the particles and ensures the delivery to the targeted cells. To optimize the design of engineered DDSs, it is essential to gain a comprehensive understanding of these core-shell assemblies at the atomic level. In this review, we illustrate how solid-state nuclear magnetic resonance (ssNMR) spectroscopy has become an essential tool in DDS design.

Indexed as

Drug Delivery SystemsNanoparticlesNuclear Magnetic Resonance, BiomolecularPolymersPolymersdrug delivery systemheteronucleiporous materialsolid-state NMR spectroscopy

Identifiers

PMID34299416
PMCPMC8306949

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.