Evidence map›Paper›PMID 34299385›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of Bis(Indolyl)Pyridines Analogues of the Marine Alkaloid Nortopsentin.

Heba M Abo-Salem, Hayam A Abd El Salam, Anhar M Abdel-Aziem, Mohamed S Abdel-Aziz, Eslam Reda El-Sawy

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  9. Review
  10. Delving into the Mechanisms of Sponge-AssociatedMolecules (Basel, Switzerland) · 2023
    Article
  11. Pyridine Compounds with Antimicrobial and Antiviral Activities.International journal of molecular sciences · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Heba M Abo-SalemChemistry of Natural Compounds Department, National Research Centre, Dokki, Giza 12622, Egypt.ORCID 0000-0003-3778-2272
Hayam A Abd El SalamGreen Chemistry Department, National Research Centre, Dokki, Giza 12622, Egypt.
Anhar M Abdel-AziemChemistry Department, Faculty of Science (Girl's Branch), Al-Azhar University, Cairo 11284, Egypt.
Mohamed S Abdel-AzizMicrobial Chemistry Department, Genetic Engineering and biotechnology Division, National Research Centre, Dokki, Giza 12622, Egypt.
Eslam Reda El-SawyChemistry of Natural Compounds Department, National Research Centre, Dokki, Giza 12622, Egypt.
National Research Centre · EGAl-Azhar University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An efficient and simple protocol for the synthesis of a new class of diverse bis(indolyl)pyridines analogues of the marine alkaloid nortopsentin has been reported. A one-pot four-component condensation of 3-cyanocarbomethylindole, various aldehyde, 3-acetylindole, and ammonium acetate in glacial acetic acid led to the formation of 2,6-bis(1

Indexed as

AlkaloidsAnti-Bacterial AgentsBacteriaBiofilmsDNA GyraseDNA Topoisomerase IVEnzyme InhibitorsIndolesMolecular Docking SimulationNucleoside-Phosphate KinasePyridinesAlkaloidsAnti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVdTMP kinaseEnzyme InhibitorsIndolesNucleoside-Phosphate KinasepyridinePyridinesantimicrobialbenzofuranbiofilm formationbis(indolyl)pyridinemolecular dockingnortopsentin

Identifiers

PMID34299385
PMCPMC8304590
OpenAlexW3178473173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.