Evidence map›Paper›PMID 34299345›Full record

ArticleInternational journal of molecular sciences2021

3D-Printed Collagen-Based Waveform Microfibrous Scaffold for Periodontal Ligament Reconstruction.

Hsu-Hsiang Lin, Pen-Hsiu Grace Chao, Wei-Chiu Tai, Po-Chun Chang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hsu-Hsiang LinGraduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei 10048, Taiwan.
Pen-Hsiu Grace ChaoDepartment of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei 10617, Taiwan.
Wei-Chiu TaiGraduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei 10048, Taiwan.
Po-Chun ChangGraduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei 10048, Taiwan.ORCID 0000-0002-4493-6922
National Taiwan University · TWKaohsiung Medical University · TW

Funding

National Health Research Institutes EX110-10810EINational Taiwan University 108L7853National Taiwan University Hospital 107-N3959, 108-S4118
6 · The paper itself

Abstract

Reconstruction of the periodontal ligament (PDL) to fulfill functional requirement remains a challenge. This study sought to develop a biomimetic microfibrous system capable of withstanding the functional load to assist PDL regeneration. Collagen-based straight and waveform microfibers to guide PDL cell growth were prepared using an extrusion-based bioprinter, and a laminar flow-based bioreactor was used to generate fluidic shear stress. PDL cells were seeded on the respective microfibers with 0 or 6 dynes/cm

Indexed as

BioprintingCell DifferentiationCell ProliferationCells, CulturedCell SurvivalCollagenCytoskeletonHumansOsteogenesisPeriodontal LigamentPrinting, Three-DimensionalStress, MechanicalTissue ScaffoldsCollagenbioprintingcollagenperiodontal ligamenttissue engineering

Identifiers

PMID34299345
PMCPMC8307958
OpenAlexW3185827197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.