Evidence map›Paper›PMID 34299235›Full record

ArticleInternational journal of molecular sciences2021

Oligomerization and Nitration of the Grass Pollen Allergen Phl p 5 by Ozone, Nitrogen Dioxide, and Peroxynitrite: Reaction Products, Kinetics, and Health Effects.

Anna T Backes, Kathrin Reinmuth-Selzle, Anna Lena Leifke, Kira Ziegler, Carola S Krevert, Georg Tscheuschner, Kurt Lucas, Michael G Weller, Thomas Berkemeier, Ulrich Pöschl and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anna T BackesMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0002-2163-8973
Kathrin Reinmuth-SelzleMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0001-7274-3848
Anna Lena LeifkeMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.
Kira ZieglerMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0003-1368-9487
Carola S KrevertMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0001-7339-2306
Georg TscheuschnerDivision 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), 12489 Berlin, Germany.ORCID 0000-0002-2311-1016
Kurt LucasMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0001-8267-7397
Michael G WellerDivision 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), 12489 Berlin, Germany.ORCID 0000-0003-2767-2029
Thomas BerkemeierMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0001-6390-6465
Ulrich PöschlMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0003-1412-3557
Janine Fröhlich-NowoiskyMultiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.ORCID 0000-0002-1278-0054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The allergenic and inflammatory potential of proteins can be enhanced by chemical modification upon exposure to atmospheric or physiological oxidants. The molecular mechanisms and kinetics of such modifications, however, have not yet been fully resolved. We investigated the oligomerization and nitration of the grass pollen allergen Phl p 5 by ozone (O

Indexed as

AllergensKineticsNitratesNitrogen DioxideNitrogen OxidesOxidantsOzonePeroxynitrous AcidPhleumPlant ProteinsPoaceaePollenProteinsRhinitis, Allergic, SeasonalAllergensNitratesNitrogen DioxideNitrogen OxidesOxidantsOzonePeroxynitrous AcidPhl p V protein, Phleum pratensePlant ProteinsProteinsdityrosinenitration degreenitrotyrosineprotein dimerprotein oligomertyrosine

Identifiers

PMID34299235
PMCPMC8303544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.