Evidence map›Paper›PMID 34299020›Full record

ReviewInternational journal of molecular sciences2021

From Supramolecular Hydrogels to Multifunctional Carriers for Biologically Active Substances.

Joanna Skopinska-Wisniewska, Silvia De la Flor, Justyna Kozlowska

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Frontiers in nutrition · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Peptide-Based Materials That Exploit Metal Coordination.International journal of molecular sciences · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Advanced injectable hydrogels for cartilage tissue engineering.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joanna Skopinska-WisniewskaFaculty of Chemistry, Nicolaus Copernicus University in Torun, Gagarin 7, 87-100 Torun, Poland.
Silvia De la FlorDepartment of Mechanical Engineering, Universitat Rovira i Virgili, Av. Països Catalans 26, 43007 Tarragona, Spain.ORCID 0000-0002-6851-1371
Justyna KozlowskaFaculty of Chemistry, Nicolaus Copernicus University in Torun, Gagarin 7, 87-100 Torun, Poland.ORCID 0000-0002-2482-339X

Funding

Narodowe Centrum Badań i Rozwoju TECHMATSTRATEG2/407770/2/NCBR/2020Narodowe Centrum Nauki UMO-2016/21/D/ST8/01705
6 · The paper itself

Abstract

Supramolecular hydrogels are 3D, elastic, water-swelled materials that are held together by reversible, non-covalent interactions, such as hydrogen bonds, hydrophobic, ionic, host-guest interactions, and metal-ligand coordination. These interactions determine the hydrogels' unique properties: mechanical strength; stretchability; injectability; ability to self-heal; shear-thinning; and sensitivity to stimuli, e.g., pH, temperature, the presence of ions, and other chemical substances. For this reason, supramolecular hydrogels have attracted considerable attention as carriers for active substance delivery systems. In this paper, we focused on the various types of non-covalent interactions. The hydrogen bonds, hydrophobic, ionic, coordination, and host-guest interactions between hydrogel components have been described. We also provided an overview of the recent studies on supramolecular hydrogel applications, such as cancer therapy, anti-inflammatory gels, antimicrobial activity, controlled gene drug delivery, and tissue engineering.

Indexed as

Anti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsBiocompatible MaterialsDelayed-Action PreparationsDrug Delivery SystemsGene Transfer TechniquesHydrogelsHydrogen-Ion ConcentrationHydrophobic and Hydrophilic InteractionsIonsLigandsPolymersTemperatureTissue EngineeringAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsBiocompatible MaterialsDelayed-Action PreparationsHydrogelsIonsLigandsPolymerscontrolled releasedrug deliverynon-covalent interactionssupramolecular hydrogels

Identifiers

PMID34299020
PMCPMC8307912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.