Evidence map›Paper›PMID 34299002›Full record

ArticleInternational journal of molecular sciences2021

Modulation of Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway by Culinary Sage (

Nancy Chiang, Shahla Ray, Jade Lomax, Sydney Goertzen, Slavko Komarnytsky, Chi-Tang Ho, John P Munafo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. American Basil,Nutrients · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nancy ChiangDepartment of Food Science, Rutgers University, New Brunswick, NJ 08901, USA.
Shahla RayDepartment of Food Science, University of Tennessee, Knoxville, TN 37996, USA.
Jade LomaxPlants for Human Health Institute, North Carolina State University, Kannapolis, NC 28081, USA.
Sydney GoertzenPlants for Human Health Institute, North Carolina State University, Kannapolis, NC 28081, USA.
Slavko KomarnytskyPlants for Human Health Institute, North Carolina State University, Kannapolis, NC 28081, USA.ORCID 0000-0003-4665-4993
Chi-Tang HoDepartment of Food Science, Rutgers University, New Brunswick, NJ 08901, USA.ORCID 0000-0001-8273-2085
John P MunafoDepartment of Food Science, University of Tennessee, Knoxville, TN 37996, USA.
North Carolina State University · USRutgers, The State University of New Jersey · USUniversity of Tennessee at Knoxville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Culinary sage (

Indexed as

AnimalsBrain-Derived Neurotrophic FactorCell Line, TumorChromatography, High Pressure LiquidGene Expression Regulation, NeoplasticGliomaMass SpectrometryPlant LeavesRatsSalvia officinalisSignal TransductionBdnf protein, ratBrain-Derived Neurotrophic Factorbenzyl 6-O-β-D-apiofuranosyl-β-D-glucoside (B6AG)brain-derived neurotrophic factor (BDNF)cognition and memory functionculinary sagesage extract

Identifiers

PMID34299002
PMCPMC8303624
OpenAlexW3182597173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.