Evidence map›Paper›PMID 34298970›Full record

ArticleInternational journal of molecular sciences2021

Genetic Modeling of the Neurodegenerative Disease Spinocerebellar Ataxia Type 1 in Zebrafish.

Mohamed A Elsaey, Kazuhiko Namikawa, Reinhard W Köster

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Mohamed A ElsaeyDivision of Cellular & Molecular Neurobiology, Zoological Institute, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.ORCID 0000-0002-9073-298X
Kazuhiko NamikawaDivision of Cellular & Molecular Neurobiology, Zoological Institute, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.
Reinhard W KösterDivision of Cellular & Molecular Neurobiology, Zoological Institute, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.ORCID 0000-0001-6593-8196
Technische Universität Braunschweig · DESuez Canal University · EG

Funding

Egypt Ministry of Higher Education and Scientific Research and Deutscher Akademischer Austauschdienst GERLS Fellowhsip
6 · The paper itself

Abstract

Dominant spinocerebellar ataxias (SCAs) are progredient neurodegenerative diseases commonly affecting the survival of Purkinje cells (PCs) in the human cerebellum. Spinocerebellar ataxia type 1 (SCA1) is caused by the mutated

Indexed as

Disease Models, AnimalAnimalsAnimals, Genetically ModifiedAtaxin-1Cell DeathDisease ProgressionExploratory BehaviorGenes, ReporterHumansLarvaLuminescent ProteinsPurkinje CellsRed Fluorescent ProteinSpinocerebellar AtaxiasTransgenesTrinucleotide Repeat ExpansionAtaxin-1ATXN1 protein, humanLuminescent ProteinsRed Fluorescent ProteinZebrafish Proteinsbioimagingcerebellumneurodegenerationpolyglutamine diseasePurkinje cellsspinocerebellar ataxia type 1zebrafish

Identifiers

PMID34298970
PMCPMC8306488
OpenAlexW3177644874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.