Evidence map›Paper›PMID 34298964›Full record

ArticleInternational journal of molecular sciences2021

Polyphenylglyoxamide-Based Amphiphilic Small Molecular Peptidomimetics as Antibacterial Agents with Anti-Biofilm Activity.

Tsz Tin Yu, Rajesh Kuppusamy, Muhammad Yasir, Md Musfizur Hassan, Manjulatha Sara, Junming Ho, Mark D P Willcox, David StC Black, Naresh Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Cholic Acid-Based Antimicrobial Peptide Mimics as Antibacterial Agents.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tsz Tin YuSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-8484-7342
Rajesh KuppusamySchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0001-9844-5064
Muhammad YasirSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0003-4589-4311
Md Musfizur HassanSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
Manjulatha SaraSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.
Junming HoSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0001-9381-924X
Mark D P WillcoxSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0003-3842-7563
David StC BlackSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0001-9300-4737
Naresh KumarSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-0951-9621

Funding

Australian Research Council DP180100845
6 · The paper itself

Abstract

The rapid emergence of drug-resistant bacteria is a major global health concern. Antimicrobial peptides (AMPs) and peptidomimetics have arisen as a new class of antibacterial agents in recent years in an attempt to overcome antibiotic resistance. A library of phenylglyoxamide-based small molecular peptidomimetics was synthesised by incorporating an

Indexed as

Anti-Bacterial AgentsPeptidomimeticsBiofilmsEscherichia coliStaphylococcus aureusStructure-Activity RelationshipSulfonylurea CompoundsAnti-Bacterial AgentsglyoxamidePeptidomimeticsSulfonylurea Compoundsantibiofilmantimicrobial peptideisatinmembrane disruptionpeptidomimeticsterphenylterphenylglyoxamide

Identifiers

PMID34298964
PMCPMC8303886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.